3.0T磁共振LAVA动态增强判断子宫内膜癌肌层浸润深度的价值  

Role of 3.0T LAVA Dynamic Enhanced MRI in Evaluation of Depth of Myometrial Invasion in Endometrial Carcinoma

作　　者：孙骏[1] 陈文新[1] 叶靖[1] 吴晶涛[1] 王守安[1] 施斌斌[1] 傅剑雄[1] 

机构地区：[1]扬州大学临床医学院,江苏省苏北人民医院医学影像科,225001

出　　处：《临床放射学杂志》2011年第11期1643-1647,共5页Journal of Clinical Radiology

摘　　要：目的探讨3.0T磁共振肝脏快速容积采集技术(LAVA)动态增强判断子宫内膜癌肌层浸润深度的应用价值。资料与方法回顾性分析52例子宫内膜癌的T2WI和LAVA动态增强图像,以手术病理结果为标准,计算两种序列诊断子宫内膜癌肌层浸润的敏感性、特异性、阳性预测值、阴性预测值和准确性。结果 T2WI判断内膜癌肌层浸润及深肌层浸润的敏感性、特异性、阳性预测值、阴性预测值和准确性分别为84.4%、71.4%、95.0%、41.7%、82.7%和63.6%、82.9%、50.0%、89.5%、78.8%。LAVA动态增强判断内膜癌肌层浸润及深肌层浸润敏感性、特异性、阳性预测值、阴性预测值和准确性分别为93.3%、85.7%、97.7%、66.7%、92.3%和90.9%、95.1%、83.3%、97.5%、94.2%。LAVA动态增强判断子宫内膜癌深肌层受侵的准确性高于T2WI诊断的准确性,差异有统计学意义(P<0.05)。结论 3.0T磁共振LAVA动态增强扫描有助于提高子宫内膜癌肌层浸润术前诊断的准确性。Objective To evaluate the value of liver acquisition with volume acceleration（LAVA） dynamic enhanced magnetic resonance imaging in the preoperative assessment of myometrial invasion in endometrial carcinoma.Materials and Methods 52 patients with histopathologically proven endometrial carcinoma were analyzed retrospectively.Both T2WI and LAVA dynamic enhanced MRI were performed in all patients.MR findings were compared with pathologic results.Sensitivity,specificity,positive and negative predictive values,diagnostic accuracy of MR imaging in depicting myometrial invasion were calculated.Results The sensitivity,specificity,positive and negative predictive values（PPV and NPV）,diagnostic accuracy for the identification of any myometrial invasion and deep myometrial invasion were 84.4%,71.4%,95.0 %,41.7%,82.7% and 63.6%,82.9%,50.0%,89.5%,78.8% on T2WI,and 93.3%,85.7%,97.7%,66.7%,92.3% and 90.9%,95.1%,83.3%,97.5%,94.2% on LAVA dynamic enhanced MRI,respectively.There was statistical difference of accuracy between two techniques for the identification of deep myometrial invasion.Conclusion 3.0 T LAVA dynamic enhanced MRI can effectively assess the depth of myometrial invasion in endometrial carcinoma.

关 键 词：子宫内膜肿瘤 磁共振成像 动态增强 

分 类 号：R737.33[医药卫生—肿瘤]