舍曲林治疗脑卒中后抑郁50例临床疗效观察  

Effects of Setraline on Post-stroke Depression:A report of 50 cases

作　　者：张国平[1] 吴文怡[1] 

机构地区：[1]北京世纪坛医院神经内科,北京市100038

出　　处：《中国全科医学》2011年第19期2175-2176,共2页Chinese General Practice

摘　　要：目的探讨舍曲林对脑卒中后抑郁症的影响。方法将50例脑卒中后抑郁患者随机分为治疗组(n=28)和对照组(n=22)。对照组采用综合治疗,治疗组在综合治疗的基础上口服舍曲林治疗。应用汉密尔顿抑郁量表(HAMD)对两组患者治疗前后进行评定。结果治疗组应用舍曲林2、4周后HAMD评分较对照组均有明显的改善,差异有统计学意义(P<0.05)。结论舍曲林治疗脑卒中后抑郁疗效显著,可提高患者的生活质量。Objective To observe the effects of setraline on post-stroke depression（PSD）.Methods A total of 50 patients with PSD were randomly divided into medicine group（n=28） and control group（n=22）.The patients in the control group received physical therapy while the patients in the medicine group received an additional setraline treatmeng.All patients were assessed with Hamilton Depression Scale（HAMD） before and after treatment.Results HAMD score in the medicine group improved remarkably after both 2-week and 4-week setraline treatment（P0.05）.Conclusion Setraline remarkably improves the conditions of patients with PSD.

关 键 词：舍曲林 脑卒中后抑郁 治疗结果 

分 类 号：R749.42[医药卫生—神经病学与精神病学]