海藻酸钙医用敷料中丙酮残留量的气相色谱法测定  

Determination of Residual Acetone of Calcium Alginate Medicinal Auxiliary by GC

作　　者：张洋[1] 蔡丽玲[1] 陈怡[1] 丁旭芬[1] 吴建一[1] 

机构地区：[1]嘉兴学院生物与化学工程学院,浙江嘉兴314001

出　　处：《嘉兴学院学报》2011年第6期61-63,共3页Journal of Jiaxing University

基　　金：浙江省大学生科技创新计划项目(2010R417036)

摘　　要：采用气相色谱法,通过氢火焰离子化检测器(FID),在柱温80℃,进样口温度160℃,检测器温度160℃,以N,N-二甲基甲酰胺(DMF)为溶剂进行丙酮残留量检测。结果显示:检测浓度在6.96μg/ml～580μg/ml内线性关系良好(r=0.99984),平均回收率99.39%.由此得出:建立的气相色谱法灵敏、准确,适合海藻酸钙医用辅料中丙酮残留量的检测.Method： The residual acetone was determined by GC with a HP--5 capillary column, with FID detector and N, N--dimethyl formamide as the solvent. The injector temperature and the detector temperate were 160℃. Result.. The calibration curve of acetone was linear in the concentration range of 6.96ug/ml- 580ug/ml, the average recovery rate was 99.39%. Conclusion： This method was simple, sensitive, accurate, and can be used for the determination of residual acetone of Ca-alginate medicinal auxiliary.

关 键 词：气相色谱法 残留量 丙酮 海藻酸钙医用敷料 

分 类 号：R914[医药卫生—药物化学]