乳腺乳头状癌17例的诊断与治疗  

Papillary carcinoma of the breast, report of 17 cases

作　　者：郑书荣[1] 郭贵龙[1] 董磊[2] 黄奇迪[1] 尤捷[1] 

机构地区：[1]温州医学院附属第一医院肿瘤外科,浙江325000 [2]温州医学院附属第一医院病理科,浙江325000

出　　处：《中华普通外科杂志》2011年第11期925-927,共3页Chinese Journal of General Surgery

基　　金：浙江省卫生厅基金资助项目（2009B106）

摘　　要：目的探讨乳腺乳头状癌的临床特征、病理和诊治。方法回顾性分析温州医学院附属第一医院收治的17例乳腺乳头状癌的临床资料。结果乳腺乳头状癌发病率占同期收治所有乳腺癌的0．64％。患者均可触及肿块。12例患者行乳腺癌改良根治术，2例行单纯乳房切除术，2例行保乳手术，1例行乳房单纯切除＋前哨淋巴结活检术。术后15例行辅助化疗，其中5例另行放射治疗。术后随访时间1个月～8年，中位随访时间为32．5个月。1例发生骨转移于术后2年死亡，1例发生多器官转移于术后7年死亡。结论乳腺乳头状癌患者的治疗及预后与其病理类型密切相关。对导管内乳头状癌的治疗宜选择低创伤的手段，对浸润性乳头状癌及浸润性微乳头状癌须按浸润性导管癌治疗原则处理。Objective To study the clinical characteristics, pathology, and treatment for papillary carcinoma of the breast. Methods The clinical data of 17 patients of papillary carcinoma of the breast admitted in the First Affiliated Hospital of Wen Zhou Medical College were retrospectively analyzed. Results Papillary carcinoma of the breast accounted for 0. 64% of all breast cancer cases hospitalized during last 10 years. All cases had palpable lumps in the breast. 12 cases received modified radical mastectomy, 2 cases received simple mastectomy, 2 cases underwent breast conservation therapy, 1 case underwent simple mastectomy plus sentinel lymph node biopsy. 15 patients received postoperative chemotherapy, among those 5 cases also received radiotherapy. During a 32. 5-month median follow-up （ 1 month to 8 years）, one case with bone metastases died 2 years postoperatively and another one died of multimetastases 7 years later. Conclusions The prognosis of papillary carcinoma of the breast is closely related with its pathology type. For intraductal papillary carcinoma low-traumatic therapy is applicable, while in case of infiltrating papillary carcinoma or invasive micropapillary carcinoma （IMPC）, more aggressive therapies like that adopted for infiltrating ductal carcinoma are recommended.

关 键 词：乳腺肿瘤 癌 乳头状 浸润性微乳头状癌 

分 类 号：R737.9[医药卫生—肿瘤]