影响胃癌根治术患者预后因素的分析  

Analysis of Prognostic Factors for Patients with Gastric Cancer after Radical Resection

作　　者：沈承澜[1] 沈振斌[2] 陈伟东[2] 

机构地区：[1]上海中医药大学附属市中医医院外科,上海200071 [2]复旦大学附属中山医院普外科,上海200032

出　　处：《中国临床医学》2011年第5期643-645,共3页Chinese Journal of Clinical Medicine

摘　　要：目的:探讨影响胃癌根治术术后的预后的相关因素。方法:回顾分析复旦大学附属中山医院普外科1999年12月—2005年12月135例胃癌根治手术患者的临床资料,用Kaplan-Meier计算3年生存率,行Log-rank单因素分析、Cox回归多因素分析探讨影响胃癌患者预后因素。结果:单因素分析显示:肿瘤部位、Borrmann分型、浸润深度、淋巴结转移、TNM分期、手术方式等影响因素与预后相关(P<0.05),多因素分析显示:TNM分期、淋巴结转移为影响胃癌患者生存的独立预后因素(P<0.05)。结论:TNM分期是影响胃癌患者预后的重要因素。Objective：To study the independent prognosis factors of gastric cancer. Methods： A retrospective clinical analysis was made in 135 cases of gastric cancer, all the patients were treated by radical gastrectomy in Zhongshan Hospital from Dec. 1999 to Dec. 2005. Kaplan-Meier survival curve was applied for survival analysis,and Log-rank test was used for univariate analysis. The Cox proportional hazard model was used for multivariate analysis. Results： The univariate analysis revealed that tumor location, Borrmann type, depth of invasion, lymph node metastasis, TNM stage were influential factors for the prognosis of patients（P〈0.05）. The multivariable Cox regression showed that TNM stage, lymph node metastasis were independent prognostic factors of gastric cancer（P〈0.05）. Conclusions： TNM stage is influential factor for the prognosis of gastric cancer.

关 键 词：胃癌 根治术 预后 

分 类 号：R735.2[医药卫生—肿瘤]