健康人胃肠道自主神经功能检查方法的评价及其意义  

Evaluation and significance of the test for gastrointestinal autonomic nervefunction in healthy subject

作　　者：赵威[1] 孙晓红[1] 方秀才[1] 王智凤[1] 班宗文[1] 柯美云[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院消化内科,北京100730

出　　处：《基础医学与临床》2011年第12期1305-1308,共4页Basic and Clinical Medicine

基　　金："十一五"国家科技支撑计划资助项目(2007BAI04B01)

摘　　要：目的本研究旨在评价健康人胃肠道自主神经功能检查方法及其意义。方法分别采用心率变异(HRV)分析及标准心血管自主神经检查,比较健康志愿者餐前、餐后自主神经功能。结果 1)健康志愿者餐后心率高于餐前。但餐前、后标准心血管自主神经功能无差异。2)HRV分析发现,健康志愿者餐后与餐前比较,交感成分增强(P<0.05),交感-副交感比例增加(P<0.05),而副交感成分减弱(P<0.01)。结论进餐联合心血管自主神经功能检查可能有助于反映胃肠道自主神经功能。HRV分析比标准心血管自主神经功能检查具有优势。Objective To evaluate gut autonomic function tests in healthy subjeets（HS） and its significance. Meth- ods Heart rate variability （HRV） analysis and standard cardiac autonomic test were performed before and after te.st meal in HS （n = 18）. Results 1 ）Though heart rate increased significantly, there was no difference between pre and postprandial autonomic function by standard autonomic test in HS. 2）Sympathetic to parasympathetic balance in- creased （P 〈 0. 05） and parasympathetic function decreased （P 〈 0. 01 ） after test meal by HRV analysis in HS. Con- dusions Test meal combined with cardiac autonomic function test may help to reflect gastrointestinal autonomic nerve function. HRV analysis combined with test meal is better than standard cardiac autonomic test.

关 键 词：健康志愿者 自主神经功能 HRV分析 标准心血管自主神经检查 

分 类 号：R57[医药卫生—消化系统]