呼吸道感染患者肺炎衣原体感染状况调查分析  

Research on Chlamydia Pneumoniae Infection in Patients with Respiratory Tract Infection

作　　者：齐海宇[1] 蒋毅[2] 郑晓燕[1] 万康林[2] 王婧[1] 肖红丽[1] 阴赪宏[1] 

机构地区：[1]首都医科大学附属北京友谊医院 [2]传染病预防控制国家重点实验室,中国疾病预防控制中心传染病预防控制所,北京102206

出　　处：《医学研究杂志》2011年第11期42-43,共2页Journal of Medical Research

基　　金：科技部重大专项基金资助项目(2008ZX10004-002);首都医学发展基金资助项目(2009-1033);北京医药卫生技术和产品重大项目培育研究项目(Z101107050210018)

摘　　要：目的了解呼吸道感染患者肺炎衣原体感染状况,为临床诊断和治疗提供依据。方法用ELISA方法对呼吸道感染患者血清进行肺炎衣原体血清抗体IgG和IgM的检测,结果采用SPSS 10.0软件包进行数据统计分析,计数资料比较用χ2检验。结果 91例呼吸道感染患者肺炎衣原体抗体IgG阳性者为58例,阳性率为63.7%;IgM阳性者为9例,阳性率为9.9%。男性和女性IgG和IgM阳性率均无统计学差异。﹤40岁组和≥40岁IgG阳性率分别为52.5%和86.7%,两者具有统计学差异;IgM阳性率分别为4.8%和14.3%,无统计学差异。结论在有呼吸道症状的病例中,肺炎衣原体感染率较高,应对肺炎衣原体感染加以重视。Objective To investigate Chlamydia pneumoniae infection in patients with respiratory tract infection and provide infor- mation for clinical diagnosis and treatment. Methods ELISA was used to detect Chlamydia pneumoniae antibodies in sera of patients with respiratory tract infection. SPSS software andx^2 test were used to analyze the results. Results Totally 91 sera from patients with respiratory tract infection were collected. 58 were positive for IgG and the positive rate for IgG was 63.7%. 9 patients were positive for IgM and the positive rate for IgM was 9.9%. No significant difference was observed in IgG and IgM positive rate between men and women. The positive rate of IgG in more than 40 - year - old group and less than 40 - year - old group was 52.5% and 86.7% respectively. The difference in positive rate of IgG was significant between two groups. The positive rate of IgM in more than 40 - year - old group and less than 40 - year - old group was 4.8% and 14.3% respectively. The difference in positive rate of IgM had no significance between two groups. Conclusion There are higher Chlamydia pneumoniae infection rate in patients with respiratory tract infection. Chlamydia pneumoniae infection should be taken seriously.

关 键 词：肺炎衣原体 呼吸道感染 ELISA 

分 类 号：R741[医药卫生—神经病学与精神病学]