颅内静脉窦血栓形成16例临床分析  

Clinical and Radiological Analysis of Crerbral Venous Sinus Thrombosis:A Review of 16 Cases

作　　者：陈莹[1,2] 郑峥[1,2] 陈德周[1,3] 

机构地区：[1]福建医科大学省立临床医学院 [2]福建省立医院神经内科,350001 [3]福建省立医院放射科,350001

出　　处：《中国临床神经科学》2011年第6期606-610,615,共6页Chinese Journal of Clinical Neurosciences

基　　金：福建省卫生厅青年课题(编号:2004-2-19)

摘　　要：目的:探讨颅内静脉窦血栓形成(CVST)的临床特点。方法:回顾性分析16例CVST患者的临床资料。结果:本组16例均为中青年患者。临床表现:头痛14例(87.5%),癫发作8例(50.0%)。9例腰穿显示脑脊液压力增高。CT显示脑静脉窦异常4/10例(40.0%);MRI显示脑静脉窦异常7/16例(43.8%)。MRV显示脑静脉窦异常15例(100%);DSA显示静脉窦异常2例(100%)。患者均予抗凝和脱水治疗,部分予溶栓治疗,好转15例,未愈1例。结论:CVST的临床特点是中青年人发生率高,以头痛等颅高压症状为主要表现;MRI+MRV及DSA确诊率高;应及时予抗凝治疗,重症患者可行溶栓治疗。Aim： To explore the clinical features of cranial venous sinus thrombosis（CVST）.Methods： The clinical data of 16 patients with CVST were retrospectively analyzed.Results： There were 16 middeaged or young patients.The clinical manifestation showed headache in 14 cases（87.5%）,epilepsy in 8 cases（50.0%）.There were 9 patients to get lumber puncture CSF examination and accompanied with high cerebrospinal fluid pressure.CT showed abnormal cerebral venous sinus in 4 cases（40.0%）.MRI showed abnormal cerebral venous sinus in 7 cases（43.8%）.MRV showed abnormal crerbral venous sinus in 15 cases（100%）;DSA showed abnormal cerebral venous sinus in 2 cases（100%）.15 patients improved and 1 patient did not improved after the treatment with anticoagulation,dehydration and endovascular intervention.Conclusion： The clinical feature of CVST is that the incidence rate is high in middle-aged and young patients.A chief manifestation is intracranial hypertension such as headache.The diagnosis rate if MRI＋MRV or DSA is high.The patients with CVST should be treated with anticoagulation in time,and severe cases can be treated by thrombolytic therapies

关 键 词：颅内静脉窦血栓形成 临床特点 治疗 

分 类 号：R743[医药卫生—神经病学与精神病学]