外周原始神经外胚叶肿瘤CT、MRI及病理分析  

CT and MR imaging and pathological analysis of peripheral primitive neuroectodermai tumor

作　　者：李文美[1] 赵欣[1] 龙莉玲[1] 黄仲奎[1] 李春燕[1] 韦敏怡[1] 

机构地区：[1]广西医科大学第一附属医院放射科,广西南宁530021

出　　处：《实用放射学杂志》2011年第11期1710-1712,共3页Journal of Practical Radiology

摘　　要：目的研究外周原始神经外胚叶肿瘤的CT、MRI表现及病理特征。方法回顾性分析经病理证实的9例外周原始神经外胚叶肿瘤的临床、影像及病理资料。4例行CT检查，5例行MRI检查。结果本组9例，上颌窦2例，胸壁2例，股骨、眼眶、椎管、肩部及腋窝各1例。8例肿瘤为单发，类圆形多见，5例为软组织肿块伴邻近骨质破坏，囊变坏死少见，未见钙化，CT平扫密度多均匀，MRI平扫为T1等肌肉信号、T2不均匀高信号，增强扫描多为明显强化。2例出现淋巴结转移。肿瘤免疫组化均表达CD99，不表达白细胞共同抗原（LCA）。结论外周原始神经外胚叶肿瘤的CT及MRI表现为非特异性，但能很好地显示肿瘤及侵袭范围，其最终诊断依靠病理和免疫组织化学检查。Objective To investigate the characteristics of CT,MR imaging and pathology of peripheral primitive neuroectodermal tumor（pPNET）. Methods The clinical,imaging and pathological findings in 9 patients with pPNET proved histopathologically were retrospectively analyzed. 4 cases and 5 cases underwent CT and MR imaging respectively. Results The lesions in 9 cases located in maxillary sinus in 2 cases, chest in 2 cases, femur, eyes, spinal, shoulder and axillary in one, respectively. Tumors were single （ n= 8 ） and oval,5 cases showed as osteolytic lesions with soft tissue mass,cystic degeneration and necrosis were rare. Of all cases,calcification inside the lesions was not seen. The tumors were showed as homogeneous density on CT and intermediate signal intensity on T2 WI, hyperintensity on T2 WI, and most of them were obvious enhancement after injection of contrast medium. Lymph node enlargement was seen in 2 cases. Tumor＇ s cells expressed positive of CD99,but not eukocyte common antigen. Conclusion CT amd MRI appearances of pPNET are not specific,but MR imaging and CT are of important value in evaluating the locaton of the tumors and the invasion of tumors,final diagnosis of pPNET depends on pathology and immunohistochemistry.

关 键 词：原始神经外胚叶肿瘤 体层摄影术 X线计算机 磁共振成像 

分 类 号：R739.43[医药卫生—肿瘤] R814.42[医药卫生—临床医学]