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作 者:汤建生
机构地区:[1]丹徒区人民医院消化内科,江苏镇江212000
出 处:《承德医学院学报》2011年第4期368-370,共3页Journal of Chengde Medical University
摘 要:目的:探讨复方苦参结肠溶胶囊联合柳氮磺胺吡啶(SASP)治疗溃疡性结肠炎(UC)的临床疗效。方法:40例轻、中度活动期UC患者随机分为两组(n=20),治疗组患者给予复方苦参结肠溶胶囊联合SASP治疗,对照组患者单纯应用SASP治疗。观察两组的治疗效果。结果:治疗组的总有效率为90%,明显高于对照组的70%(P<0.05);治疗组患者治疗后主要症状(腹痛、腹泻、粘液血便、里急后重)的改善情况明显优于对照组(P<0.05)。结论:复方苦参结肠溶胶囊联合SASP治疗UC效果显著,优于单用SASP。Objective:To investigate the therapeutic effects of coloniccoated compound lightyellow sophora root capsules combined sulfasalazine (SASP) in treatment of ulcerative colitis (UC) patients.Methods:40 patients with mild or moderate UC (active phase) were randomly divided into 2 groups with 20 patients in each group. The patients in treatment group were given coloniccoated compound lightyellow sophora root capsules combined SASP; while the patients in control group were treated by SASP only. The therapeutic effects of 2 groups were observed after treatment.Results:The total effective rate of treatment group was 90%, which was obviously higher than that of control group (70%,P〈 0.05). The main symptoms of UC (include abdominal pain, diarrhea, mucus bloody stool and tenesmus) were obviously improved for patients in treatment compared with control group (P〈 0.05).Conclusions:Combination of coloniccoated compound lightyellow sophora root capsules and SASP can get obvious therapeutic effects in treatment of UC and is better than using SASP only.
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