乳腺叶状肿瘤临床病理分析  

Clinicopathological analysis of breast phyllodes tumor

作　　者：陈昌伟[1] 果海娜[1] 李良[1] 黄锦叶[1] 肖亚芳[1] 

机构地区：[1]中山大学附属东华医院病理科,广东东莞523220

出　　处：《泰山医学院学报》2011年第10期738-740,共3页Journal of Taishan Medical College

摘　　要：目的探讨乳腺叶状肿瘤(PTs)的临床病理学特点。方法对38例乳腺PTs患者的临床资料进行回顾性分析。结果乳腺PTs大体上均表现为界限清楚的肿块,且呈分叶状。肿瘤由具有双层排列的上皮成分以及过度生长的间质成分组成。根据间质的过度生长程度、细胞的异型程度、核分裂数、有无异源性成分以及肿瘤性坏死等继发性改变将其分为良性、交界性和恶性3个级别。结论乳腺PTs病理学形态分为三级:良性、交界性和恶性,容易误诊,免疫组织化学对恶性PTs的诊断有一定帮助,从良性到恶性均容易复发,治疗上首选手术扩大切除。Objective： To study the pathological features of the breast phyllodes tumor（PTs）. Methods： Thirty -eight cases of breast hyUodes tumor were analyzed by retrospective study. Results： The appearance of every breast phyllodes tumor was well - demarcated and lobulated. The tumor consisted of double layer epitheliums and stromal overgrowth. The breast phyllodes tumor could be classified as benign, borderline and malignant according to the secondary changes such as the degree of stromal overgrowth and heterotype of cell, the number of nuclear fission, heterology components, tumor necrosis, and so on. Conclusion： The pathological appearances of the breast phyllodes tumor include three types： benign, borderline and malignant, so it is misdiagnosed easily. Immunohistochemistry is helpful for the diagnosis of the malignant breast phyllodes tumor. The benign or malignant breast phyllodes tumor recurs easily. The broad excision is preferred for breast phyllodes tumor.

关 键 词：乳腺 叶状肿瘤 病理 

分 类 号：R737.9[医药卫生—肿瘤]