Activity of the Fungicide JS399-19 Against Fusarium Head Blight of Wheat and the Risk of Resistance  

作　　者：CHEN Yu WANG Wen-xiang ZHANG Ai-fang GU Chun-yan ZHOU Ming-guo GAO Tong-chun 

机构地区：[1]Institute of Plant Protection, Anhui Academy of Agricultural Sciences, Hefei 230031, P.R.China [2]College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, P.R.China

出　　处：《Agricultural Sciences in China》2011年第12期1906-1913,共8页中国农业科学（英文版）

基　　金：sponsored by the National Natural Science Foundation of China (30971891);the Natural Science Foundation of Jiangsu Province, China(BK2008337);the Anhui Provincial Natural Sci-ence Foundation,China (10040606Q26)

摘　　要：This report reviews the characteristics of JS399-19, a novel cyanoacrylate fungicide. JS399-19 strongly inhibits the mycelial growth of the fungal plant pathogens of the genus Fusarium and exhibits great potential in controlling Fusarium head blight （FHB） on wheat and other cereals. The mode of action of JS399-19 is evidently different from that of benzimidazole （for example, carbendazim） and other sort of fungicides, making it a possible replacement for carbendazim in China to manage carbendazim-resistant subpopulations of Fusarium graminearum and F. asiaticum. JS399-t9 has excellent protective and curative activity against these pathogens. Incorrect use of this fungicide, however, is likely to select for resistance. Among JS399-19-resistant mutants of F. asiaticum induced in the laboratory, the resistant level of mutants was high and the phenotype of resistance against JS399-19 was conferred by a major gene by genetic analysis. The fitness of laboratory-induced JS399-19-resistant mutants of F. asiaticum was nearly equal to that of their parents. JS399-19 lacks cross resistance with other sort fungicides. To control FHB with JS399-19 and to delay the development of the fungicide-resistance, farmers should use tank mixtures containing JS399-19 and carbendazim, metconazole, tebuconazole, or prothioconazole.This report reviews the characteristics of JS399-19, a novel cyanoacrylate fungicide. JS399-19 strongly inhibits the mycelial growth of the fungal plant pathogens of the genus Fusarium and exhibits great potential in controlling Fusarium head blight （FHB） on wheat and other cereals. The mode of action of JS399-19 is evidently different from that of benzimidazole （for example, carbendazim） and other sort of fungicides, making it a possible replacement for carbendazim in China to manage carbendazim-resistant subpopulations of Fusarium graminearum and F. asiaticum. JS399-t9 has excellent protective and curative activity against these pathogens. Incorrect use of this fungicide, however, is likely to select for resistance. Among JS399-19-resistant mutants of F. asiaticum induced in the laboratory, the resistant level of mutants was high and the phenotype of resistance against JS399-19 was conferred by a major gene by genetic analysis. The fitness of laboratory-induced JS399-19-resistant mutants of F. asiaticum was nearly equal to that of their parents. JS399-19 lacks cross resistance with other sort fungicides. To control FHB with JS399-19 and to delay the development of the fungicide-resistance, farmers should use tank mixtures containing JS399-19 and carbendazim, metconazole, tebuconazole, or prothioconazole.

关 键 词：fungicide JS399-19 cyanoacrylate fungicide Fusarium head blight ACTIVITY resistance risk 

分 类 号：S435.121.4[农业科学—农业昆虫与害虫防治] S482.2[农业科学—植物保护]