双麻茶毒理学安全性评价  

Toxicology and Safety Assessment of Shuangma tea

作　　者：何秀菊[1] 游剑[1] 李高同[2] 

机构地区：[1]江西中医学院中药固体制剂制造技术国家工程研究中心,南昌330006 [2]江西农业大学,南昌330045

出　　处：《江西中医学院学报》2011年第4期47-49,共3页Journal of Jiangxi College of Traditional Chinese Medicine

摘　　要：目的:对双麻茶的食用安全性进行食品毒理学安全性评价和研究。方法:进行小鼠经口急性毒性试验、Ames试验、小鼠骨髓嗜多染红细胞微核试验、小鼠精子畸形试验。结果:双麻茶小鼠经口MTD﹥20 g/kg.bw,属无毒级;Ames试验、骨髓微核试验及小鼠精子畸形试验表明该样品无致突变作用,对雄性生殖细胞无遗传毒性。结论:双麻茶属无毒级物质,对体细胞无致诱变及突变作用。Objective： To evaluate and study the toxicological safety of Shuangma tea.Methods： Acute toxicity test,Ames test,bone marrow micronucleus test,sperm malformation test were conducted.Results：Shuangma tea with the dose of MTD﹥20 g/kg.bw showed to be non-toxic on the mice.Ames test and bone marrow micronucleus test and sperm malformation test showed Shuangma tea was safe without mutagenesis.No toxicity was observed in sperm shape abnormality test in mice.Conclusion： Shuangma tea is a non-toxic and non-mutating drug for the body cell.

关 键 词：双麻茶 毒理学安全性 评价 

分 类 号：R285.5[医药卫生—中药学]