MEMS白血病细胞介电电泳芯片的研究  

Study on Leukemia-cell Dielectrophoresis Microchip Based on MEMS

作　　者：赵志强[1,2] 赵德春[1] 曾翰庆[2] 庞宇[1] 王伟[1] 李章勇[1] 

机构地区：[1]重庆邮电大学生物医学工程研究中心,重庆400065 [2]重庆医科大学附属第二医院,重庆400010

出　　处：《压电与声光》2011年第6期1002-1005,共4页Piezoelectrics & Acoustooptics

基　　金：中华人民共和国工业和信息化部专项[工信部科(2011)353号]基金资助项目

摘　　要：研究了白血病细胞介电电泳芯片,其核心结构由绝缘覆盖层、电极层和绝缘垫层构成。该文对该芯片中的微电极进行了电场力学分析,讨论并设计了芯片的各个参数,应用微机电系统(MEMS)技术成功制备芯片,并对芯片进行了双列直插式DIP封装。文中研究的白血病细胞介电电泳芯片具有微型化,低电压驱动,对细胞无化学毒害等优点。The leukemia-cell dielectrophresis microchip based on MEMS technology has been studied in this work.The core of the leukemia-cell dielectrophoresis microchip is made up of the insulating cover,electrodes layer and insulating underlay.The micro-electrode of the microchip has been analyzed through the electric field mechanics.The various parameters of the microchip have been discussed and designed.The leukemia-cell dielectrophoresis microchip has been fabricated successfully by using MEMS technology and the chip was packaged by DIP method.The proposed leukemia-cell dielectrophoresis microchip has the good features of miniaturization,low-voltage driving and no chemical poisoning on the cells.

关 键 词：微机电系统 白血病 介电电泳 芯片 电场 

分 类 号：R318[医药卫生—生物医学工程]