晚期胃癌姑息性术后血管介入性灌注化疗联合静脉化疗与单纯静脉化疗效果分析  

The Analysis of Vascular Interventional Perfusion Chemotherapy Combined with Intravenous Chemotherapy and Pure Intravenous Chemotherapy after Palliative Operation of Patients with Advanced Gastric Carcinoma

作　　者：李永标 

机构地区：[1]广西崇左市人民医院外科三病区,广西崇左532200

出　　处：《河北医学》2011年第12期1576-1579,共4页Hebei Medicine

摘　　要：目的:探讨晚期胃癌姑息性术后血管介入性灌注化疗联合静脉化疗的临床疗效。方法:回顾性分析37例胃癌姑息性术后血管介入性灌注化疗联合静脉化疗(观察组)和26例单纯静脉化疗(对照组)的临床病理资料,比较两组之间的临床疗效。结果:观察组化疗有效率为81.1%(30/37),对照组化疗有效率为53.8%(14/26),两组之间疗效比较具有统计学意义(P<0.05)。两组之间化疗反应比较没有显著性差异(P>0.05)。观察组1年及3年生存率分别为86.5%和35.1%;对照组1年及3年生存率分别为57.7%和19.2%,两组之间比较差异具有统计学意义(P<0.01)。结论:晚期胃癌姑息性术后血管介入性灌注化疗联合静脉化疗的临床疗效显著优于单纯静脉化疗,值得在临床上推广应用。Objective： Discuss the clinical effect of vascular interventional perfusion chemotherapy combined with intravenous chemotherapy after palliative operation for patients with advanced gastric carcinoma.Method： 37 cases treated with vascular interventional perfusion chemotherapy combined with intravenous chemotherapy after palliative operation for patients with advanced gastric carcinoma were taken as the group of observation.And 26 cases treated with pure intravenous chemotherapy were taken as the group of control.The two groups were analyzed through review and compared in their clinical effects.Result： Effectiveness ratio of chemotherapy for the group of observation reached 81.1 %（30/37） and that of the group of control reached 53.8 %（14/26）.Comparison in curative effects of the two groups was of statistical significance（P0.05）.No significant difference was found in the chemotherapy reaction between the two groups（P0.05）.One-year and three-year survival rates for the group of observation were 86.5% and 35.1% respectively,and those for the group of control were 57.7% and 19.2% respectively.The comparison between the two groups was of statistical significance（P0.01）.Conclusion： Clinical curative effect of vascular interventional perfusion chemotherapy combined with intravenous chemotherapy after palliative operation for patients with advanced gastric carcinoma is superior to that of pure intravenous chemotherapy and is thus worth promotion in clinical application.

关 键 词：胃癌 姑息性手术 介入性化疗 静脉化疗 

分 类 号：R735.2[医药卫生—肿瘤]