综合干预措施对恢复期精神分裂症患者认知功能的作用对照研究  

The synthesis intervention measure cognition function's function comparison studies to recovery period schizophrenia sickness patient the

作　　者：郑德明[1] 张衍军[1] 李西敏[1] 徐喜云 马照红 董玉军[1] 

机构地区：[1]山东省济宁市荣复军人医院,山东兖州272101

出　　处：《中国民康医学》2011年第23期2976-2978,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:探讨综合干预措施对精神分裂症患者认知功能的作用。方法:采用随机数字表将98例精神分裂症患者随机分为行为干预组(49例)和对照组(49例),在维持原有抗精神病药物治疗的同时,由专职精神科医师对综合干预组进行干预,对照组仅为定期随访,干预及随访期限为1年。于入组时及1年末分别对两组患者进行阳性症状与阴性症状量表(PANSS)、威斯康星卡片分类试验(WCST)及瑞文标准推理测验(SPM)进行精神症状及认知功能的评定。结果:综合干预前、后研究组在PANSS总分[(47.21±11.78)与(42.26±10.78),t=2.17,P<0.05]、PANSS阴性症状因子分[(15.18±2.28)与(12.46±3.36),t=5.67,P<0.01];WCST在持续错误数[(29.3±10.48)与(20.10±11.29),t=4.05,P<0.01;分类数(4.84±1.31)与(4.09±1.28),t=2.78,P<0.05];SPM在知觉辨别[(3.89±2.84)与(6.61±3.12),t=4.37,P<0.01],类同比较[(4.28±2.07)与(7.87±2.67),t=7.05,P<0.01];比较推理[(3.97±1.64)与(6.43±2.34),t=5.84,P<0.01];系列关系[(4.04±2.34)与(7.48±3.08),t=6.03,P<0.01];抽象推理[(3.49±1.17)与(5.67±1.83),t=6.81,P<0.01]等因子存在统计学显著差异。结论:综合干预可以明显改善患者的阴性症状,并使大脑执行功能和抽象思维能力明显改善。Objective：Discussion synthesis intervention measure to schizophrenia sickness patient cognition function function. Methods ：Uses the stochastic tables to divide into stochastically 98 example schizophrenia sickness patient the behavior intervention group （49 examples） and the control group （49 examples）, During maintenance original anti -neurosis pharmacological treatmeut＇s, carries on the behavior intervention by professional neurology department doctor to the intervention group, the control group is only the regular revisit, the intervention and the revisit deadline is one year. When Yu Ruzu and one end of the year carries on the masculine symptom and the negative symptom meter separately to two group of patients （ PANSS ）, the Wisconsin card sorting experiment （WCST） and the auspicious article standard inference examination （SPM） carries on the energetic symptom and the cognition function evaluation. Results： Intervenes the before and after study team in the PANSS total score [ （47.21 ± 11.78） and （42.26 ± 10.78）, t = 2.17, P 〈 0.05, the PANSS negative symptom factor divides （ 15.18 ± 2.28） and （ 12.46 ± 3.36）, t = 5.67, P 〈 0.01 ] ; WCST is continuing the wrong number [ （29.3 ± 10.48） and （20.10 ± 11.29）, t =4.05, P 〈0.01 ; Classified number （4.84 ± 1.31 ） and （4.09±1.28）, t=2.78, P〈0.05]; SPM in consciousness discernment [（3.89_±2.84） and （6.61 ±3.12）, t=4.37, P〈 0.01 ], is similar the comparison [ （4.28 ± 2.07 ） and （ 7.87 ± 2.67 ）, t = 7.05, P 〈 0.01 ] ; Compared with inference [ （ 3.97± 1.64） and （6.43±2.34）, t=5.84, P〈0.01]; Series relations [（4.04±2.34） and （7.48±3.08）, t=6.03, P〈0.01]; Ab- stract inference [ （3.49 -± 1.17 ） and （ 5.67 ± 1.83 ）, t = 6.81, P 〈 0.01 ] and so on factor existence statistics remarkable differences. Conclusions： The synthesis intervention may improve patient＇s negative symptom obviously, and causes the cerebrum to carry out the function a

关 键 词：综合干预 精神分裂症 认知功能 

分 类 号：R749.3[医药卫生—神经病学与精神病学]