双径路泵控动脉灌注化疗防治胃肠道肿瘤复发及肝转移  

Study Gastrointestinal of Cancer Recurrence and Hepatic Metastasis by Two Pathway Pump controlling Perfusion Chemotherapy

作　　者：王仁忠[1] 徐震壮[1] 蔡兵[1] 李建平[1] 顾晓峰[1] 丁忠阳[1] 

机构地区：[1]无锡市第一人民医院,无锡214002

出　　处：《苏州医学院学报》1999年第12期1298-1299,1458,共3页Acta Academiae Medicinae Suzhou

摘　　要：目的　探讨双径路动脉灌注化疗防治肿瘤局部复发及肝转移的价值。方法　全组２５ 例，在切除胃肠道肿瘤的同时，应用微泵技术，最大耐受剂量，对原肿瘤供血区域的动脉主干插管置泵灌注化疗，同时进行预防肝转移的肝动脉插管置泵化疗。结果　经临床观察和随访１０～２４ 个月，随访期病例全部存活，均未发现肿瘤局部复发和肝转移，胃肠道肿瘤主要标志物放射免疫测定２２／２３ 例在正常范围。结论　双径路动脉置泵灌注化疗防治中晚期胃肠道肿瘤局部复发和肝转移效果良好。Objective To investigate the value of two pathway perfusion chemotherapy to prevent gastrointestinal cancer recurrence and hepatic metastasis.Methods Pump controlling perfusion chemotherapy with micropump technique and maximal tolerant dosage applied was performed in 25 cases of gastrointestinal cancer being resected by inserting catheter through the main artery supplying blood to the region of the tumors as well as hepatic artery to prevent hepatic metastasis.Results All patients survived and no local recurrence and hepatic metastasis were observed during 10～24 months.At the same time major tumor markers in 24 of 25 cases of gastrointestinal cancer were normal.Conclusion Application of two pathway pump controlling perfusion chemotherapy in the patients of intermediate or advanced gastrointestinal cancer is effective safe and convenient to prevent the cancer local recurrence and hepatic metastasis.

关 键 词：双径路 动脉泵灌注 胃肠道肿瘤 肝转移 

分 类 号：R735.05[医药卫生—肿瘤] R73－37[医药卫生—临床医学]