跨声门癌与声门上癌的组织病理学比较研究  

Histopathological Comparative Study Between Transglottic Carcinoma and Supraglottic Carcinoma

作　　者：曹志伟[1] 潘子民[1] 于靖寰[1] 费声重[1] 关超[1] 于刚[1] 

机构地区：[1]中国医科大学第一临床学院耳鼻咽喉科,沈阳110001

出　　处：《中国医科大学学报》1999年第6期462-464,共3页Journal of China Medical University

摘　　要：目的：探讨跨声门癌与声门上癌的差异。方法：５０例跨声门癌及１００例声门上癌喉全切除标本，ＨＥ染色，光镜观察。结果：跨声门癌主体位于喉室或以喉室为中心向声门上区、声门区以基本均等态式浸润扩展。粘膜下深层浸润方式占５２％（２６／５０）。声门旁间隙受累为８２％（４１／５０），呈以喉室为中心的对称性浸润。甲状软骨受累率为５２％（２６／５０）；声门上癌主体位于喉室以上的声门上区。粘膜下深层浸润方式占９％（９／１００）。声门旁间隙受累为４８％（４８／１００），呈非对称性浸润。会厌软骨受累２８％（２８／１００）。结论：跨声门癌在临床、病理等诸多方面不同于声门上癌，应列为独立型的跨声门喉癌。Objective: Our paper was designed to explore the difference between transglottic carcinoma and supraglottic carcinoma. Methods: Laryngectomy specimens of 50 transglottic carcinoma and 100 supraglottic carcinoma were subjected to whole-organ serial section, HE staining and microscopic observation.Results: The main lesion of transglottic carcinoma was in the ventricle or the ventricle was the center of the lesion. Transglottic carcinoma invaded and spreaded in a way that equally involved the supraglottic and glottic regions. The rate of deep submucosal invasion was 52% (25/50). The rate of paraglottic space (PGS) invasion, which was a symmetrical invasion with the ventricle as the center, was 82% (41/50). The rate of thyroid cartilage involved was 52% (26/50). The main lesion of supraglottic carcinoma was in supraglottic region. The rate of deep submucosal invasion was 9% (9/100). The rate of PGS invasion, which is a non-symmetrical invasion, was 48%(48/100). The rate of epiglottic cartilage invaded was 28% (28/100). Conclusion:Transglottic carcinoma was different from supraglottic carcinoma in many aspect of clinical expression and histopathology and should be taken as an independent type of laryngeal carcinoma.

关 键 词：跨声门癌 声门上癌 病理学 肿瘤浸润 

分 类 号：R739.650.2[医药卫生—肿瘤]