基于Mimics软件虚拟人膝关节三维图像融合实验  

Image fusion of three dimensional knee joint from virtual human project based on Mimics software

作　　者：吴辉群[1] 严培培[1] 耿兴云[1] 张远鹏[1] 吕广明[2] 韩笑[2] 季达峰[2] 蒋葵[1] 董建成[1] 

机构地区：[1]南通大学医学院医学信息学系,南通大学数字医学研究所,江苏省南通市226001 [2]南通大学医学院人体解剖学系,江苏省南通市226001

出　　处：《中国组织工程研究与临床康复》2011年第48期8943-8946,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：南通市重大科技创新专项项目(XA200901),课题名称:基于社区医疗卫生服务的居民健康档案应用平台研究~~

摘　　要：背景:国内外已有学者利用不同的方法对人体膝关节进行三维建模,根据各自研究侧重点不同,在方法和最终效果上各有不同。目的:根据不同模态中膝关节影像的特点,将膝关节建模结果进行配准、融合,为进一步生物力学研究提供一种方便的方法。方法:采用MimicsV10.0软件根据膝关节在CT和MR断层图像的特点,选择不同分割算法进行膝关节解剖组织分割,并对不同的分割图像进行三维重建。结果与结论:基于逆向工程原理,利用虚拟人膝关节连续CT断面图像分别重建出膝关节的骨性结构如股骨、胫骨、腓骨、髌骨;并利用膝关节的连续MRI断面图像重建出半月板、髌韧带、内侧副韧带、前交叉韧带、后交叉韧带等结构,并成功对上述结构进行融合,融合后的三维膝关节模型可以任意角度或单独观察,并可以进行体视学测量。说明通过不同模态图像融合的方法可以建立膝关节的三维模型,为计算机辅助膝关节损伤康复研究奠定基础。BACKGROUND：Scholars in home and abroad have been used different methods for three-dimensional（3D） modeling of the human knee joint,according to their different focuses,the ultimate effect and methods were different.OBJECTIVE：To make registration and fusion of reconstructed knee joint according to the characteristics from different modality images,which provides a convenient method for further biomechanics research.METHODS：Different segmentation algorithms were implemented to different knee joint tissues according to the characteristics of image from CT and MR modalities using Mimics V 10.0.3D reconstructions of different segmented images were performed,and the results were registered and fused.RESULTS AND CONCLUSION：Based on reverse engineering principle,the bony structures such as femur,tibia,fibula,patella were reconstructed from CT serial sections,and meniscus,patellar ligament,medial collateral ligament,anterior cruciate ligament,posterior cruciate ligament were reconstructed from MR serial images.The reconstructed structures were successfully fused,and could be observed at any angle or observed individually,and could be measured.It is indicated that 3D models of knee joint based on image fusion from different modality images,which provides basis for research on computer-aided knee joint injury rehabilitation.

关 键 词：数字医学 虚拟人 三维重建 图像融合 膝关节 

分 类 号：R318[医药卫生—生物医学工程]