新型控暴剂辣椒素的致伤效应研究进展  

Wounding effects of capsaicin,a new irritant riot control agent:an overview

作　　者：骆媛[1] 王永安[1] 

机构地区：[1]军事医学科学院毒物药物研究所,北京100850

出　　处：《国际药学研究杂志》2011年第6期432-437,共6页Journal of International Pharmaceutical Research

基　　金：国家"重大新药创制"科技重大专项(2011ZXJ09305-06)

摘　　要：新型控暴剂辣椒素作为催泪瓦斯的主要组分,已被广泛装备于军队及警察部门,用于制止暴力犯罪和各种恐怖活动等。辣椒素可引起流泪、喷嚏、咳嗽等强烈不适症状或受累器官的疼痛,导致中毒人员暂时性失能。虽然辣椒素被认为是相对安全的控暴剂,但其诱发的严重并发症甚至死亡等中毒事件,不得不使人们重新认识其安全性。目前国内外对辣椒素的致伤效应研究非常有限,相关医学防护急救措施更是缺乏,本文将就辣椒素的毒理学作用及防护措施研究进展作一综述。Capsaicin,a new irritant agent as the main component of tear gas or pepper spray,is being widely used by army or police forces to aid in arresting aggressive individuals. When applied in the form of a spray,it quickly produces lacrimation, sneezing,cough,as well as pain in some organ after stimulation,that can cause exposed persons incapacitated. In general,pepper spray appears to be a relatively safe weapon with small risk.,but serious complications and even deaths have been reported, and raises questions and concerns regarding its health effects and safety. Not enough is known concerning the toxic effects of this riot control agent thus far,and also lack of medical protective measures. This article will review the toxicological effects of the new irritant agent capsaicin,and the research progress of its medical protective measures.

关 键 词：辣椒素 催泪瓦斯 毒理学作用 防护措施 

分 类 号：E929[军事—军事装备学]