SPECT/CT断层融合显像在分化型甲状腺癌^(131)I治疗后的应用价值  

Value of fused imaging of SPECT/CT in patients with differentiated thyroid carcinoma after ^(131)I therapy

作　　者：刘永[1] 宋长祥[1] 陆武[1] 杜鹏[1] 

机构地区：[1]连云港市第一人民医院核医学科,江苏连云港222002

出　　处：《海南医学》2011年第24期93-95,共3页Hainan Medical Journal

摘　　要：目的评价SPECT/CT断层融合显像在分化型甲状腺癌131I治疗后的应用价值。方法分化型甲状腺癌(DTC)术后患者49例,于131I治疗后5~7d行SPECT/CT全身平面显像(WBS)和局部断层融合显像,诊断结果与病理或其他影像检查及临床随访结果对比,分析其灵敏度及准确率。结果平面显像发现异常摄碘疑诊为转移灶40处,灵敏度、准确率分别为76.09%(35/46)、68.63%(35/51);断层显像发现异常摄碘诊断为转移灶45处,灵敏度、准确率分别为93.48%(43/46)、89.58%(43/48)。结论 DTC患者131I治疗后,SPECT/CT断层融合显像诊断转移灶的效能明显优于平面显像,SPECT/CT断层融合显像对DTC术后转移的诊断有较高的应用价值。Objective To explore the clinical value of fused imaging of SPECT/CT in patients with differentiated thyroid carcinoma （DTC） after ^131Ⅰ therapy. Methods 49 patients with DTC accepting ^131Ⅰ therapy after thyroid surgery underwent planar whole-body scan （WBS） and SPECT/CT fused imaging. The diagnostic performance of WBS and SPECT/CT were comparatively analyzed compared with the pathology or other examinations and follow-up results. The sensitivity and the accuracy were calculated and analyzed respectively. Results SPECT/CT fused imaging found the remains of thyroid gland and metastasis lesion＇s location, range and numbers accurately. The sensitivity and the accuracy of ^131Ⅰ WBS and SPECT/CT for detecting the metastasis were 76.09% （35/46）, 68.63% （35/51）and 93.48% （43/46）, 89.58%（43/48）, respectively. Conclusion ^131Ⅰ-SPECT/CT fused imaging has more important diagnostic value than routine nuclear medicine planar imaging for patients with DTC after ^131Ⅰ therapy.

关 键 词：分化型甲状腺癌 碘放射性同位素 单光子发射计算机断层 融合显像 

分 类 号：R736.1[医药卫生—肿瘤]