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作 者:高俊珍[1] 付秀华[1] 李国华[1] 徐常丽[1] 王立红[1]
机构地区:[1]内蒙古医学院附属医院呼吸内科,呼和浩特010050
出 处:《中日友好医院学报》2011年第6期338-341,共4页Journal of China-Japan Friendship Hospital
基 金:内蒙古自然科学基金2011MS1122
摘 要:目的:探讨老年肺癌患者的临床特点及支气管镜表现。方法:回顾分析416例经支气管镜确诊的老年肺癌患者(年龄≥60岁)的临床资料及支气管镜检查结果,并与327例非老年肺癌患者(年龄〈60岁)进行对比分析。结果:老年肺癌患者男女比例是3.9:1,中位年龄是68岁,咯血症状显著多于非老年患者(P〈0.05)。鳞癌最多见,占50.5%,显著多于非老年(P〈0.01);其次是小细胞癌,占19.7%,显著少于非老年(P〈0.01)。支气管镜下以增生型病变最多,占72.1%(300/416),其次是浸润型,占21.9%(91/416)。老年增生型的鳞癌最多见,占42.8%(178/416),显著高于非老年患者(P〈0.05)。肺CT显示的病变部位与支气管镜检查结果的符合率是54.2%~77.4%。结论:老年肺癌患者的临床症状、病理分型及支气管镜下表现与非老年肺癌患者存在差异;支气管镜检查是临床上诊断老年人肺癌的重要手段。Objective:To explore the clinical characteristics and bronchoscopy features of elderly patients with lung cancer.Methods:A total of 416 elderly patients(age over 60 years)of lung cancer diagnosed with bronchoscopy and 327 young and middle-aged patients of lung cancer were analyzed retrospectively.The correlations among the histopathologic type of lung cancer,chest CT scan,symptom,gender and the features under bronchoscope were investigated.Results:Of the elderly patients,the male/female ratio was 3.9/1,and the median age was 68.The number of elderly patients with hemoptysis was higher than that of young and middle-aged group(P0.05).The pathological types included squamous cell carcinoma(n=210,50.5%),small cell lung cancer(n=82,19.7%)and adenocarcinoma(n=71,17.1%).Among the patients with squamous cell cancer,elder was significantly more than young and middle-aged group(P0.01).While among the small cell lung cancer,elder was significantly lower than young and middle-aged group(P0.01).Under bronchoscope,the cases consisted of proliferative neoplasm(n=300,72.1%),infiltration(n=91,21.9%)in elderly patient with lung cancer.Most lesions were found in elderly patients with squamous cell carcinoma of neoplasm(n=178,42.8%)that was significantly more than young and middle-aged group(P0.05).The conformity range of CT and bronchoscopy was 54.2%~77.4% in elderly patients of lung cancer.Conclusion:The number of elderly patients with squamous cell carcinoma of neoplasm is higher than that of young and middle-aged people,and bronchoscopy plays an important role in the diagnosis of lung cancer in elderly patients.
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