急性脑梗死血管内个体化溶栓治疗  

Individualized intraarteral thrombolysis treatment and control of the risk factors related to it in the patients with acute cerebral infarct(analysis of 68 cases)

作　　者：陈焕雄[1] 夏鹰[1] 李钢[1] 颜山[1] 李智勇[1] 于正涛[1] 

机构地区：[1]海口市人民医院神经外科,570208

出　　处：《中国临床神经外科杂志》2011年第12期717-719,722,共4页Chinese Journal of Clinical Neurosurgery

基　　金：海南省卫生厅科学研究课题(琼卫2010-78)

摘　　要：目的探讨动脉溶栓治疗急性脑梗死的疗效及其安全性。方法选择急性发病且在12h内的脑梗死病人68例,采用不同方式机械性动脉溶栓,通过脑血管造影判断其血管开通情况并对其治疗疗效进行评估。结果 68例急性脑梗死患者中血管完全再通率58.8%(40/68),部分再通率为35.3%(24/68),未开通4例,占5.9%;临床治愈42例(61.8%),显著好转16例(23.5%),有效6例(8.8%),无效4例(5.8%);本组无死亡病例。结论经动脉溶栓是治疗急性脑梗死的一种安全有效的方法;建立急救绿色通道和规范其治疗措施,能较好的提高急性脑梗死患者救治的成功率,降低死亡率和致残率。Objective To explore the tactics of treatment of acute cerebral infarct （ACI） by different mechanical intraarteral thrombolyses and their effects on ACI. Methods The different mechanical intraarteral thrombolyses were performed in 68 patients with ACI within 12 hours after ACI attack. The therapeutic effects were assessed by cerebral angiography. Results The rates of complete recanalization of the occluded cerebral vessels were 58.8% （40/68）, and partial 35.3% （24/68）, and no recanalization of the occluded cerebral vessels was found in 4 （5.9%） patients. Of 68 patients with ACI, 42 （61.8%） were cured, 16 （23.5%） improved significantly, 6 （8.8%） improved partially and 4 （5.8%） unchanged. No patients died. Conclusion The treatment of ACI by different mechanical intraarteral thrombolyses was safe and effective. The curative effect of the mechanical intraarterial thrombosis on ACI can be enhanced by setting up the first aid system and standard therapeutic measure.

关 键 词：急性脑梗死 动脉溶栓 疗效 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R815.2[医药卫生—临床医学]