糖皮质激素治疗特发性视神经炎是否有效  

Is it efficacy for the treatment of idiopathic optic neuritis with glucocorticosteroid

作　　者：张秀兰[1] 王伟[1] 魏世辉[2] 

机构地区：[1]中山大学中山眼科中心眼科学国家重点实验室,广州510060 [2]解放军总医院眼科

出　　处：《中华眼科杂志》2011年第12期1062-1064,共3页Chinese Journal of Ophthalmology

摘　　要：糖皮质激素（以下简称激素）是治疗重要神经眼科疾病的主要措施之一。然而长期以来，激素治疗特发性视神经炎是否有效一直是争论的焦点。笔者认为应权衡利弊，结合患者的视功能、MRI等检查情况给出个体化的治疗方案，对于类似美国视神经炎治疗试验中特发性视神经炎的患者应采用其推荐方案。不建议局部注射治疗。目前激素应用仍有许多临床问题尚待解决，也缺乏足够的证据用于参考，亟待国内开展有关激素治疗神经眼科疾病规范化的多中心、随机临床试验，并出版规范的临床诊治指南或共识。Glucocorticosteroid （steroid） therapy is the major treatment for some important neuro- ophthalmological diseases. However, its efficacy, safety and abuse raise great controversy and debate for a long time, many clinical problems also remain to be solved. This paper discusses the issues relevant to the treatment of idiopathic optic neuritis by steroid and strongly advocate carrying out an evidence-based multicenter randomized clinical trial in China. It is suggested to establish a standard guideline or consensus for the treatment of neuro-ophthalmological diseases with steroid.

关 键 词：视神经炎 糖皮质激素类 

分 类 号：R774.6[医药卫生—眼科]