239例经纤维支气管镜确诊肺癌的临床特点分析  

Clinical characterization analysis of 239 cases of lung cancer diagnosed by bronchofibroscopy

作　　者：李兰英[1] 谭杰[1] 关向群[1] 王虹[1] 

机构地区：[1]广东药学院附属第一医院呼吸内科,广东广州510080

出　　处：《临床肺科杂志》2012年第1期91-94,共4页Journal of Clinical Pulmonary Medicine

摘　　要：目的评价经纤维支气管镜确诊的不同病理类型肺癌的镜下表现及临床特点。方法我院经纤维支气管镜确诊的239例肺癌,对其病理类型与纤支镜下病变特点、病变部位、年龄、性别、吸烟等之间关系进行分析。结果 239例肺癌中,鳞癌占46.0%,腺癌占23.0%,腺鳞癌占2.1%,小细胞癌占16.7%,其他肺肿瘤占12.1%;管腔生长型改变是最常见的肿瘤生长方式,占63.6%,且多为鳞癌;肺癌多侵犯1个部位,占93.7%,鳞癌、腺癌、小细胞癌等侵犯肺上叶多于下叶;男性鳞癌的发病率最高,占50.3%,女性腺癌发病率最高,占45.2%;肺癌的发病年龄在40岁以上增加,50～69岁为发病高峰,70岁以后开始下降;男性鳞癌患者吸烟率达75.8%,腺癌吸烟率为69.4%,小细胞癌患者吸烟率最高,占80%。结论不同病理类型的支气管肺癌的镜下表现及临床特点均有所不同,但存在一定规律。Objective To evaluate the images under the bronchofibroscope and the clinical characteristics of different histological types of lung cancer diagnosed by bronchofibroscopy. Methods We retrospectively analyzed the pathological presentation, the sign and location under bronchofibroscope and the gender, age, smoking in 239 cases of lung cancer diagnosed by bronchofibroscopy in our hospital during January, 1997 to November, 2010. Results In the 239 cases, the proportion of squamous cell carcinoma was 46.0%, adenocarcinoma was 23.0%, adenosquamous carcinoma was 2. 1%, small cell lung cancer was 16. 7% and others were 12. 1%. The type of hyperplasia in bronchus was the most frequent tumor growth pattern with the proportion 63.6%, and mostly by squamous cell carcinoma. The majority tumor confined one side of lung, and the proportion was 93.7%. The squamous cell carcinoma, adenocarcinoma and small cell lung cancer located more frequently in the upper lobe than lower lobe. The predominant pathological type in this investigation was squamous cell carcinoma in male, and adenocarcinoma in female, with the incidence 50. 3% and 45.2% , respectively. The incidence of lung cancer was significantly increased in patients of age over 40 years old, the peak level of incidence at the age from 50 to 69, and then decreased at age over 70. Male smoking rate was 75.8% in squamous cell carcinoma patients, 69.4% in adenocareinoma, 80% in small cell lung cancer. Conclusion Different histological types of lung cancer has different clinical characteristics and different features under the bronchofibroscope, but there is some regularity in it.

关 键 词：肺癌 纤维支气管镜 鳞癌 腺癌 小细胞癌 

分 类 号：R734.2[医药卫生—肿瘤]