放大色素结肠镜识别直肠异常隐窝病灶的可靠性及准确性  

Reliability and accuracy of the magnification chromoendoscopy in the identification of aberrant crypt foci

作　　者：张伟[1] 王芳军[1] 钱建忠[1] 李世兰[1] 刘鹏飞[1] 

机构地区：[1]东南大学医学院附属江阴医院消化内科,江苏江阴214400

出　　处：《实用临床医药杂志》2011年第23期52-53,66,共3页Journal of Clinical Medicine in Practice

摘　　要：目的系统评估放大色素结肠镜(MCE)判断直肠异常隐窝病灶(ACF),尤其是伴异型增生ACF的可靠性及准确性。方法将内镜识别的ACF与活检病理学结果做对照研究,预测经病理学结果证实的内镜下伴异型增生ACF的可靠性。结果 MCE识别病理性伴异型增生ACF病变的正确百分率为88.1%,灵敏度为81.8%,特异度为89.0%。结论 MCE对判断结直肠ACF病变有较高的病理符合率,接近病理诊断,可避免过度活检,具有较高临床应用价值。Objective To evaluate the accuracy and reliability of various endoscopic criteria used to identify ACF, especially ACF with dysplasia when using magnification chromoendoscopy （MCE）. Methods Images obtained via MCE were shown to participating endoscopists who diag- nosed them as ACF or not. The predictive ability of ACF with dysplasia for histologic confirmation, and their reliability across endoscopists were compared. Results The correct percentage of MCE i- dentified pathological lesions of ACF with dysplasia was 88.1%, sensitivity 81.8 %, specificity 89. 0 %. Conclusion Magnifying chromoscopy is valuable in detection of ACF colorectal lesion, and has high efficacy in judging the nature of lesions with Kudo criteria. Thus MCE could guide clinical practice and avoid excessive biopsy to some extent.

关 键 词：放大色素结肠镜 直肠异常隐窝病灶 活检病理学 

分 类 号：R574.6[医药卫生—消化系统]