进展性缺血性脑卒中与颈动脉粥样硬化的关系  

Relationship between progressive ischemic stroke and carotid artery atherosclerosis

作　　者：刘逾前[1] 朱丹[2] 吕淑萍[2] 吕晓红[2] 

机构地区：[1]吉林省前卫医院神经内科,吉林长春130012 [2]吉林大学白求恩第一医院神经内科,吉林长春130021

出　　处：《中风与神经疾病杂志》2011年第12期1086-1089,共4页Journal of Apoplexy and Nervous Diseases

基　　金：吉林省卫生厅资助项目(No.20082093)

摘　　要：目的探讨进展性缺血性脑卒中与颈动脉粥样硬化的关系。方法选取2010年6月～2010年12月入住吉林大学白求恩第一医院的进展性缺血性脑卒中患者50例(A组)及非进展性脑梗死患者50例(B组),用彩色多普勒超声对所有患者进行双侧颈总动脉及颈内动脉探查。结果动脉斑块最易在颈总动脉分叉处形成,两组比较无显著差异,P>0.05;A组颈动脉粥样硬化斑块中不稳定斑块多于B组,P<0.05;A组患者中、重度颈动脉粥样硬化例数多于B组,P<0.05;A组患者中、重度颈动脉狭窄例数多于B组,P<0.05。结论进展性缺血性脑卒中与非进展性缺血性脑卒中颈动脉粥样硬化斑块都最易发生在颈总动脉分叉处;颈动脉粥样硬化不稳定斑块与进展性缺血性脑卒中关系密切,可能是导致脑梗死早期进展的重要危险因素;进展性缺血性脑卒中重度颈动脉粥样硬化及重度颈动脉狭窄明显高于非进展性脑梗死,也是发生进展性缺血性脑卒中的危险因素。Objective To explore the relationship between carotid artery atherosclerosis and progressive ischemic stroke.Methods From June 2010 to December 2010,50 progressive ischemic stroke patients（Group A） and 50 non-progressive ischemic stroke patients（Group B） in the First Hospital of Jilin University were selected for the study.The common and internal carotid arteries of the patients were examined by color Doppler ultrasound.Results Carotid atherosclerotic plaques typically formed at carotid artery bifurcation.There was no significant difference between the two groups,P0.05.In group A,unstable plaques occured more frequently than in group B,P0.05.Severe carotid atherosclerosis was more in progressive than in non-progressive ischemic stroke patients,P0.05.Severe carotid stenosis occured more frequently in progressive than in non-progressive ischemic stroke patients,P0.05.Conclusion Carotid atherosclerotic plaques typically form at carotid artery bifurcation in both progressive and non-progressive ischemic stroke patients.Unstable carotid atherosclerotic plaques are closely related to progressive ischemic stroke,and might be an important risk factor leading to early progress in cerebral infarction.Severe carotid artery atherosclerosis and stenosis are more significantly in progressive than in non-progressive ischemic stroke patients,and they are risk factors for progressive ischemic stroke.

关 键 词：颈动脉粥样硬化 进展性缺血性脑卒中 彩色多普勒超声 

分 类 号：R743.34[医药卫生—神经病学与精神病学]