前列腺癌患者治疗前后PSA水平  

The levels of serum prostate-specific antigen after treatment in prostate carcinoma

作　　者：陈燕[1] 徐培玉[1] 黄建英[1] 

机构地区：[1]福建省肿瘤医院,福州350014

出　　处：《中国肿瘤临床与康复》2000年第1期30-31,共2页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的　探讨PSA在前列腺癌临床诊疗中的应用价值。方法　采用ELISA法测定 3 3例健康者、3 6例良性前列腺增生及 3 3例前列腺癌治疗前后T PSA和F PSA并动态观察 2 0例放疗后T PSA水平变化。结果　前列腺癌T PSA和F PSA、F/T均显著高于良性前列腺增生 (P <0 .0 1) ;前列腺癌治疗后T PSA和F PSA显著下降 (P <0 .0 1) ,而F/T无明显改变 (P >0 .0 5 ) ;前列腺癌放疗后病情稳定T PSA下降 ,病情进展则T PSA升高。结论　动态测定前列腺癌患者治疗前后PSA水平变化 ,可判断近期疗效 ,监测病情变化。? Objective To search the clinical significance of detecting the levels of serum prostate specific antigen in monitoring the response to the treatment for prostate carcinoma.Methods The levels of serum total prostate specific antigen and free prostate specific antigen were detected by ELISA in 33 cases of prostate carcinoma before and after combined therapy,36 cases of benign prostate hyperplasia and 33 cases of control.Results The levels of serum T PSA,F PSA and the ratio of F/T in PC were significantly higher than those in BPH;The levels of serum T PSA were reduced while the disease was stabilized and increased while disease progressed in PC after radiotherapy.Conclusions The measuring of serum PSA during follow up is helpful in monitoring PC progress. 〔

关 键 词：前列腺肿瘤 综合治疗 前列腺特异性抗原 

分 类 号：R737.25[医药卫生—肿瘤]