阿魏酸稀土配合物的合成及抗凝血性能研究  

Study on Synthesis and Anticoagulant Performance of Rare Earth Complexes of Ferulic acid

作　　者：宋玉民[1] 卞常鑫[1] 王璞玉[1] 

机构地区：[1]西北师范大学化学化工学院,甘肃兰州730070

出　　处：《化学与生物工程》2011年第12期32-34,共3页Chemistry & Bioengineering

基　　金：甘肃省教育厅资助项目(1101-05)

摘　　要：采用溶剂热法,以阿魏酸与稀土氯化物RECl3.6H2O(RE=Nd3+、Ce3+、Eu3+)为原料在乙醇溶液中合成阿魏酸稀土配合物。采用傅立叶红外光谱分析、紫外可见吸收光谱分析、差热-热重分析等对配合物进行了表征,推测其结构为(C10H9O4)3RE.3H2O。同时对配体阿魏酸及其配合物的抗凝血性能进行了比较,结果发现,阿魏酸稀土配合物同阿魏酸一样具有延长凝血时间的作用,且抗凝血效果更好;3种配合物中阿魏酸钕的抗凝血性能最好。Three rare earth complexes were obtained by the reaction of ferulic acid with REC13 . 6HzO（RE =Nd3＋ ,Ce3＋ ,Eu3＋） in ethanol solution by solvent-thermal method. The complexes were characterized by IR, UV-Vis,TGA-TDA and the structure was regarded as（C10 HgO4）aRE . 3H20. Meanwhile, the anticoagulant perfomance of ferulic acid and its complexes were compared. The results showed that the complexes all had anti- coagulant performance as ferulic acid, even their anticoagulant effects were stronger. In addition, the neodymium ferulate had the best anticoagulant performance among the three complexes.

关 键 词：阿魏酸 稀土离子 配合物 抗凝血性能 

分 类 号：O614.33[理学—无机化学] R284.3[理学—化学]