促纤维组织增生性小圆细胞肿瘤的诊断与治疗模式探讨  

The study in diagnosis and therapy of desmoplastic small round cell tumor

作　　者：车德海[1] 李晓梅[1] 张华[1] 于雁[1] 

机构地区：[1]哈尔滨医科大学附属第三医院肿瘤内科,哈尔滨150081

出　　处：《实用肿瘤学杂志》2011年第6期551-554,共4页Practical Oncology Journal

摘　　要：目的 探讨DSRCT促纤维组织增生性小圆细胞肿瘤（DSRCT）的诊断及治疗模式,提高临床医生对于本病的认识.方法 收集哈尔滨医科大学附属第三医院2000年1月-2010年5月收治的3例DSRCT患者的临床资料,结合国内外文献对DSRCT的诊断和治疗模式进行分析.结果 1例男患未经治疗,诊断4个月后死亡;另外2例经过异环磷酰胺,依托泊苷和顺铂方案化疗后,分别在10～14个月死亡.结论 DSRCT预后差,目前以手术、化疗为主要的治疗方法,但效果有限,因此综合治疗模式有待于进一步摸索.Objective Desmoplastie small round cell tumor（DSRCT） is a rare and highly aggressive ma- lignant neoplasm. So the diagnosis of DSRCT is difficult, and the prognosis of DSRCT is very poor. Through the study in diagnosis and therapy of DSRCT, doctor can know it very well. Methods Three patients with DSRCT were diagnosed and treated in our hospital from January 2000 to May 2010. Acourding to the domestic and foreign literature,the study investigate the diagnosis and therapy of desmoplastic small round cell tumor. Results One boy didn＇t get any chemotherapy, and he died after diagnosis for 4 months, the other two died from 10 - 14 months after few cycles chemotherapy combined Ifosfamide with Etoposide and Cisplatin. Conclusion The prognosis of DSRCT is poor. Now, the main method in DSCRT is chemotherapy and surgery, but the effect is limit. So the deep investigation is necessary in integrated treatment mode of DSRCT.

关 键 词：促纤维组织增生性小圆细胞肿瘤 诊断 治疗 

分 类 号：R738.6[医药卫生—肿瘤]