270例脂肪肝患者中医辨证分型与血脂关系的分析  

Analysis of syndromes feature and correlation between syndromes and blood fat in 270 patients with fatty liver

作　　者：田立群[1] 胡伟[2] 石拓[2] 张书[2] 时昭红[2] 李桂珍[2] 

机构地区：[1]武汉市第一医院心内科,武汉430022 [2]武汉市第一医院消化科,武汉430022

出　　处：《天津中医药》2011年第6期463-465,共3页Tianjin Journal of Traditional Chinese Medicine

基　　金：武汉市卫生局科研基金项目(WZ08B09)

摘　　要：[目的]通过流行病问卷调查,归纳270例脂肪肝患者常见中医证型探讨脂肪肝主要证型与血脂的关系。[方法]对在本院就诊的确诊为脂肪肝的患者,进行中医辨证分析,明确证型,并进行总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)及低密度脂蛋白(LDL-C)的检测。[结果]270例脂肪肝患者中,主要证型有肝郁脾虚型、肝肾阴虚型、脾虚湿阻型、肝气郁滞型;血脂分析表明,肝肾阴虚型TC明显升高(P<0.05),肝郁脾虚型和脾虚湿阻型TG升高明显(P<0.05),脾虚湿阻型和肝郁气滞型LDL-C升高明显(P<0.05),HDL-C的比较无统计学差异;脂肪肝程度比较,重度脂肪肝TC、TG、LDL-C均明显升高(P<0.05)。[结论]在B超初步诊断脂肪肝的基础上,联合血脂指标的检测可为脂肪肝中医辨证分型提供参考依据,又可作为脂肪肝病情监控和疗效评估的有效手段。[Objective] To sum up the common syndromes in patients with fatty liver in Wuhan and the proportion of each syndrome, explore the syndromes feature and the correlation between the main syndrome and blood fat by questionnaire. [Methods] The patients in hospital diagnosed as suffering from fatty liver were analyzed by TCM syndrome differentiation and the syndrome type was identified. TC, TG, HDL-C and LDL-C were measured. [Results] In Wuhan, the main type of syndrome was stagnation of liver Qi and spleen deficiency syndrome, yin deficiency of liver and kidney syndrome, spleen deficiency and dampness retention syndrome and stagnation of liver Qi syndrome in patients with fatty liver. The analysis of blood fat indicated that the level of TC in syndrome of liver and kidney Yin deficiency was significantly increased （P〈0.05）, the level of TG in syndrome of stagnation of liver Qi and spleen deficiency and syndrome of spleen deficiency and dampness retention was significantly increased （P〈0.05）, the level of LDL-C in syndrome of spleen deficiency and dampness retention and syndrome of stagnation of liver Qi was increased significantly （P〈0.05）, and there was no significant difference of HDL-C level. The TC, TG and LDL-C levels in the fatty liver cases were much higher than those cases without fatty liver （P〈0.05）. [Conclusion] Based on the preliminary diagnosis of fatty liver by B ultrasound the combination with blood fat inspection can provide reference evidence for TCM syndrome differentiation, and can also be an effective method for supervising the disease condition and evaluating the therapeutic effect.

关 键 词：脂肪肝 中医辨证分型 血脂指标 

分 类 号：R575.5[医药卫生—消化系统]