血管性认知障碍无痴呆患者SPECT脑血流显像特点  

Image analysis of SPECT in patients with VCIND

作　　者：王兆平[1] 王文静[1] 王前友 程义壮[2] 刘学公[2] 洪波[2] 金晓毛[2] 姚晓波[2] 张然[2] 徐俊健[3] 孙一兵[4] 曾飞雁[4] 

机构地区：[1]安徽医科大学附属省立医院神经内科 [2]安徽医科大学附属省立医院核医学科 [3]安徽省立体定向神经外科研究所,合肥230001 [4]安徽医科大学附属省立医院影像科

出　　处：《安徽医科大学学报》2012年第1期78-81,共4页Acta Universitatis Medicinalis Anhui

摘　　要：目的应用单光子发射计算机断层核素显像(SPECT)探讨血管性认知障碍无痴呆(VCIND)与局部脑血流量(rCBF)的关系。方法对VCIND患者和对照组进行一般检查、神经功能评定和脑SPECT检查。结果与对照组比较,VCIND组双侧额叶、左侧顶上小叶、左侧丘脑rCBF明显降低(P<0.05);左侧额叶、左侧顶上小叶、左侧丘脑均较右侧rCBF明显降低(P<0.05)。结论 SPECT脑灌注显像对早期发现VCIND患者具有极其重要的意义。Objective To investigate the relationship of regional cerebral blood flow （rCBF） and vascular cognitive impairment, no dementia（VCIND） by single photon emission computed tomography（SPECT）. Methods VCIND patient and the control group underwent laboratory examinations, neuropsychological assessments and brain SPECT perfusion imaging. Results Compared with the control group,the rCBFs in the bilateral frontal lobe, the left superior parietal lobule and left thalamus in the VCIND group were significantly reduced（P 〈 0. 05 ）. The rCBFs of the left frontal lobe, the left superior parietal lobule and left thalamus were lower than that of the right in the VCIND group （ P 〈 0. 05 ）. Conclusion The brain SPECT perfusion imaging have important value in early detection of VCIND.

关 键 词：血管性认知障碍 脑血流量 发射型计算机体层显像中 

分 类 号：R743.9[医药卫生—神经病学与精神病学] R445.6[医药卫生—临床医学]