清热化湿凉血解毒法对亚急性肝衰竭患者血清胆红素和凝血酶原活动度的影响  

Effects of Qingrehuashi Liangxuejiedu Therapy on Serum Bilirubin and PTA of Patients with Subacute Liver Failure

作　　者：孙凤霞[1] 张强[1] 

机构地区：[1]首都医科大学附属北京地坛医院,北京100015

出　　处：《辽宁中医杂志》2012年第1期104-105,共2页Liaoning Journal of Traditional Chinese Medicine

基　　金：北京市中医药科技基金项目(JJ2008-001)

摘　　要：目的:评价清热化湿、凉血解毒法治疗亚急性肝衰竭患者肝功能的影响。方法:按是否接受中药治疗将2004-2010年北京地坛医院收治的79例亚急性肝衰竭病例分为中药组与对照组,观察患者不同时间段血清胆红素和凝血酶原活动度变化规律。结果:治疗10周末,中药组血清胆红素下降至171μmol/L以下的比例为75%、对照组为51.06%;中药组凝血酶原活动度升至40%以上的累积百分比为84.38%、对照组为61.70%。两组比较均有显著差异,P<0.05。结论:采用清热化湿、凉血解毒法治疗亚急性肝衰竭可加速黄疸消退,促进凝血功能恢复,改善肝功能。Objective：To evaluate the effects of Qingrehuashi Liangxuejiedu therapy on liver function of patients with subacute liver failure. Methods ：79 cases of subacute liver failure in Beijing Ditan hospital during 2004 -2010 were divided into two groups （the Chinese medicine group and the control group） according to whether treated with Chinese Medicine or not, and respectively described the change tendency of serum bilirubin and PTA at different periods. Results：After ten weeks of treatment ,75% of the patients in the Chinese Medicine group reduced TBIL below 171umol/L, while 51.06% in the control group;and 84. 38% of the patients in the Chinese medicine group raised PTA to 40%, while 61.70% in the control group. The difference is significant,P 〈 0. 05. Conclusion： Qingrehuashi Liangxuejiedu treatment can speed up the decline of bilirubin and the recovery of blood coagulation disorder and improve liver function of patients with SLF.

关 键 词：亚急性肝衰竭 清热化湿 凉血解毒 

分 类 号：R575.3[医药卫生—消化系统]