代谢组学在胃肠肿瘤诊断中的应用  

Diagnostic application of metabonomics in gastrointestinal cancer

作　　者：张霞[1] 王杰军[1] 

机构地区：[1]上海第二军医大学长征医院肿瘤科,200070

出　　处：《国际肿瘤学杂志》2012年第1期48-50,共3页Journal of International Oncology

摘　　要：代谢组学是继基因组学、转录组学和蛋白质组学之后发展起来的一门新的组学方法，因其独特的优势，已广泛应用到肿瘤诊断生物标志物的筛选之中。目前利用代谢组学方法在胃肠肿瘤患者组织、血液、尿液、粪便中已发现了一些诊断相关生物标志物，有助于胃肠恶性肿瘤的早期诊断及个体化治疗。Metabonomics is a novel subject which develops after genomics, transcriptomics and proteomics. With its unique advantage, metabonomics has been used widely in screening diagnostic biomarker in a variety of tumors. At present, some diagnostic biomarkers are found in tissue, serum samples, urine samples and stool specimens of gastrointestinal cancer patients by metabonomics, which maybe helpful for the early diagnosis and individualized treatment of gastrointestinal cancer.

关 键 词：胃肠肿瘤 肿瘤标记 生物学 诊断 

分 类 号：R735[医药卫生—肿瘤]