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机构地区:[1]上海交通大学医学院附属瑞金医院口腔科,上海200025
出 处:《上海口腔医学》2011年第6期590-594,共5页Shanghai Journal of Stomatology
基 金:上海交通大学医学院自然科学基金(757)
摘 要:目的:通过对微种植体-骨组织界面的组织形态学分析,研究不同加载时机对微种植体支抗稳定性的影响。方法:全麻下将48枚微型钛金属种植体植入2只实验Beagle犬双侧上、下颌骨,每只24枚。将48枚种植体分为8组,1组为对照组,负载力值为0g;其余7组为加力组,负载力值为200g。加力组分别在植入术后即刻、第1周、第2周、第3周、第4周、第5周和第6周,用正畸专用镍钛螺旋拉簧对各组微种植钉在相应的时间施加200g的水平拉力。在种植钉植入术后的第6周、第8周和第10周,分别对2只实验犬颈部皮下注射荧光剂四环素、土霉素和钙黄绿素溶液。于植入术后第12周处死实验犬,应用光学显微镜及病理图像分析系统对种植体骨磨片进行纵断面观察,并计算各种植植体-骨界面的骨结合率。各组的骨结合率数据采用SPSS13.0软件包进行统计学处理。结果:不同时机加载各组的骨沉积率与对照组无显著差异。普通光镜下可见种植体-骨界面既有骨结合又有纤维结合,不同时机加载各组的骨结合率无显著差异。结论:植入后不同时机对微种植体支抗加力不会影响其稳定性。PURPOSE:To evaluate the stability of the miniscrew on different loading time as orthodontic anchorage.METHODS: 2 healthy adult male Beagle dogs were used in this study.48 mini-implants were implanted into the maxilla and mandible of the dogs.The miniscrews were divided into 8 different groups,1 group was loaded 0g as control group and the others were loaded 200g forces as experimental groups.200g forces were loaded on the corresponding mini-implant anchorages immediately after implantation and at the time of 1w,2w,3w,4w,5w and 6w after implantation.The dogs were sacrificed at 12w after implantation.Histological progresses of implant-bone interfaces was examined with light microscope.Blue deposition and contact ratio were calculated and analyzed using SPSS13.0 software package.RESULTS:Fibrous and osseous-integration was noted in the interface,there was no significant difference in bone deposition ratio and bone contact ratio.CONCLUSION: Different force loading time does not affect the stability of the mini-implant anchorage.Supported by Natural Science Foundation of Shanghai Jiao Tong University School of Medicine(757).
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