17例眼眶血管外皮瘤的临床诊断和疗效观察  

Clinical diagnosis and curative effect observation of seventeen patients hemangiopericytoma in orbit

作　　者：丁莹[1] 张虹[1] 宋国祥[1] 

机构地区：[1]天津医科大学第二医院眼科,300211

出　　处：《中华眼科杂志》2012年第1期47-51,共5页Chinese Journal of Ophthalmology

摘　　要：目的探讨17例眼眶血管外皮瘤的临床表现、影像学特征、诊断方法及治疗原则。方法回顾性系列病例研究。对天津医科大学第二医院眼科1980至2009年共29年间17例眼眶血管外皮瘤患者的临床资料进行回顾性分析。结果眼球突出为就诊的主要原因，14例可触及眶区无痛性肿物；B超显示肿瘤边界清楚，多呈类圆形或形状不规则，内回声多少及分布与病变组织结构有关，彩色多普勒血流显像多显示肿瘤内供血丰富，部分可探及肿瘤内血管血流为动脉频谱、CT显示病变多呈均一高密度块影，并有明显强化的特点等。所有病例均行手术切除并经病理检查证实。结论眼眶血管外皮瘤是一类潜在恶性肿瘤，组织病理学分类与其临床表现和预后缺乏相关性；影像学检查有助于病变的定性定位及手术方案的制定，但缺乏特征性表现；最终诊断需依靠病理学检查；完整手术切除仍是目前最佳的治疗方法；所有病例均需密切随访。Objective To conclusion the clinical features and image features, the diagnosis and management of orbital hemangiopericytoma, in order to direct clinical diagnosis and differential diagnosis. Methods Seventeen patients with pathologically confirmed orbital hemangiopericytoma were analyzed retrospectively. Results Patients usually complained of exophthalmos. Fourteen patients can be touched the tumor in the orbit. In B-scan ultrasound, a well outlined lesion was revealed. The type of it was often similarly circular or anomaly. The extent of internal echo was associated with histological structure of lesion. Color doppler flow imaging show that the tumor has rich feeding vessels. Some of them is arterial feeding vessels. On CT scan, hemangiopericytoma generally appears to be a uniform high-density mass with obvious enhancement upon injection of contrast material. All cases underwent surgical resection and are proved by pathological examination. Conclusions Orbital hemangiopericytoma is a potentially malignant tumor. The prognosis and clinical behavior can＇t be predicted on the basis of their histopathologic classification. Medical imaging can help to demonstrate the site, configuration, and characteristics of the tumors and contribute to the treatment. But, there has not characteristic medical features. The final diagnosis must be depend on the pathology. The best management of hemangiopericytoma is complete local excision. All the patients must be observed nearly.

关 键 词：眶肿瘤 血管外皮细胞瘤 回顾性研究 

分 类 号：R739.7[医药卫生—肿瘤]