胰腺癌调强计划和三维适形计划剂量学比较与分析  

To Compare and Analyze Three Dimention Conform Radiotherapy Plan and Intensity-modulated Radiotherapy Plan for Pancreas Carcinoma

作　　者：尚进[1] 李东[1] 杨斌[1] 

机构地区：[1]沈阳军区总医院放射治疗科,辽宁沈阳110015

出　　处：《中国医学物理学杂志》2012年第1期3108-3110,共3页Chinese Journal of Medical Physics

摘　　要：目的:通过比较分析胰腺癌三维适形治疗计划(3DCRT)和调强治疗计划(IMRT),确定患者选择合适的放射治疗方式。方法:对10例胰腺癌的病人分别制定三维适形和调强治疗计划,对它们计划的靶区剂量分布和危及器官的躲避进行评估。结果:IMRT放疗计划中十二指肠的V40、V30、V20分别比3DCRT降低44.51%、10.58%、15.53%,左肾的V30、V20分别比3DCRT降低29.57%、16.18%,而小肠、脊髓、右肾、胃等危及器官的受量差别不大。结论:和三维适形治疗计划相比,调强治疗计划能有效地降低危及器官的高剂量区,有靶区剂量的提升空间。Objective： To confirm appropriate treatment method for pancreas carcinoma patients,through comparing and analyzing three dimention conform radiotherapy paln （3DCRT） and intensity-modulated radiotherapy paln（IMRT）. Methods： Select 67 pancreas carcinoma patients,establish three dimention conform radiotherapy plan and intensity-modulated radiotherapy plan respectively,evaluate target volumn dose distribute and spare normal tissue of the two plans. Results： When compare with 3DCRT, V40,V30 and V20 of duodenum in IMRT were reduce 44.51%, 10.58% and 15.58% ,V30 and V20 of left kidney in IMRT were reduce 29.57% and 16.18%, respectively. No statistically significant differences were found between 3DCRT and IMRT for dose distributions of the small bowel,cord,right kidney and stomach. Conclusions： Compared with threee dimention conform radiotherapy plan,intensity modulate radiotherapy plan can reduce the dose of organ at risks, and can enhance the dose of target volume.

关 键 词：胰腺癌 三维适形放疗 调强放射治疗 剂量学 治疗计划 

分 类 号：R730.55[医药卫生—肿瘤]