恶性浆膜腔积液200例细胞学检验的临床分析  

Clinical Analysis on Cytology Exam of Serous Effusions in 200 Patients with Malignant Tumors

作　　者：刘蕴霞[1] 刘玉侠[1] 钟政荣[1] 张伦军[1] 

机构地区：[1]安徽省蚌埠医学院第一附属医院检验科,233004

出　　处：《中华全科医学》2012年第1期111-112,共2页Chinese Journal of General Practice

摘　　要：目的对200例恶性浆膜腔积液进行回顾性研究,分析临床资料及细胞形态,以总结经验,提高恶性浆膜腔积液检出率及细胞学诊断水平。方法对200例恶性浆膜腔积液进行8个年龄组的划分归类以及镜下阅片,观察分析各型恶性肿瘤的特征。结果 200例恶性浆膜腔积液中包括76例恶性腹水,111例恶性胸水,13例恶性心包积液。76例恶性腹水,高发年龄组在50～59岁(27例)及60～69岁(22例),恶性肿瘤的类型以腺癌所占比例最高有71例(占93.4%),3例恶性淋巴瘤(占3.9%),1例肝癌(占1.3%),1例恶性黑色素瘤(占1.3%);111例恶性胸水,高发年龄组在50～59岁(23例)及60～69岁(31例),恶性肿瘤的类型以腺癌所占比例最高有105例(占94.5%),鳞癌2例(占1.8%),恶性淋巴瘤2例(占1.8%),恶性黑色素瘤1例(占0.9%),恶性胸膜间皮瘤1例(占0.9%);13例恶性心包积液,高发年龄组集中在40～49岁(3例)及50～59岁(5例),恶性肿瘤的分型以腺癌为主占12例(92.3%),另外1例为恶性淋巴瘤。结论浆膜腔积液细胞学检查,对于肿瘤的诊断、分型、预后评价具有重要意义。Objective To improve the detection rate and cellular diagnosis level of the malignant serous cavity effusion through analyzing a retrospective study of 200 cases of cytology exams.Methods Two hundred patients with malignant serous cavity effusion were divided into 8 groups according to their age.The characteristics of malignant tumors were analyzed under microscopy.Results In all 200 cases,76 were with malignant ascites,111 with malignant hydrothorax and 13 with malignant hydropericardium.As for malignant ascites,the two groups whose age ranged from 50 to 59 years old（27/76） and from 60 to 69 years old（22/76） were with highest incidence rate;the main histopathologic type of tumor was adenocarcinoma（71/76）,the other types including malignant lymphoma（3/76）,liver cancer（1/76） and malignant melanoma（1/76）.As for malignant hydrothorax,the two groups whose age ranged from 50 to 59 years old（23/111） and from 60 to 69 years old（31/111） were with highest incidence rate,the main histopathologic type of tumor was adenocarcinoma（105/111）,the other types including squamous cell carcinoma（2/111）,malignant lymphoma（2/111）,malignant melanoma（1/111） and malignant pleural mesothelioma（1/111）.With regard to malignant hydropericardium,the two groups whose age ranged from 40 to 49 years old（3/13） and from 50 to 59 years old（5/13） were with highest incidence rate,the main histopathologic type of tumor in this group was adenocarcinoma（12/13）,the remaining one is malignant lymphoma（1/13）.Conclusion The cytology exam for serous cavity effusion is of important significance for diagnosis,classification and prognosis evaluation of tumor.

关 键 词：浆膜腔积液 细胞学 肿瘤 

分 类 号：R730.21[医药卫生—肿瘤]