蛇胆菠萝蛋白酶肠溶薄膜衣片的制备工艺研究及质量考察  

Study on Preparing Process and Quality of Film Enteric-Coated Tablets of Snack-bile Bromelain

作　　者：李燕华[1] 蒋伟杰[2] 聂倩庆 

机构地区：[1]广东医学院附属三水医院,广东佛山528100 [2]广东省江门市新会人民医院,广东江门529100 [3]广东省江门市新会卫生学校,广东江门529100

出　　处：《临床医学工程》2012年第1期24-25,共2页Clinical Medicine & Engineering

基　　金：江门市科技计划项目(江科[2005]88号;项目编号8)

摘　　要：目的制备蛇胆菠萝蛋白酶肠溶薄膜衣片。方法用丙烯酸树脂Ⅱ号作肠溶衣材料,制备蛇胆菠萝蛋白酶肠溶薄膜衣片,并考察其质量稳定性。结果制备的肠溶薄膜衣片质量稳定,达到肠溶片相关要求。结论该工艺简单可靠,肠溶薄膜衣片达到《中国药典》2010年版的要求。Objecave To prepare snack-bile bromelain film enteric-coated tablets. Methods The tablets were film-coated with enteric acrylic resin Ⅱ , and investigated in quality. Results The emetic-coated tablets were better in stability, achieving the relevant requirements. Conclusion The preparation process is simple and reliable, and the enteric-coated tablets can meet the requirements of Chinese Pharmacopoeia 2010 Edition.

关 键 词：菠萝蛋白酶 薄膜衣片 制备工艺 

分 类 号：R780.2[医药卫生—口腔医学] R446.5[医药卫生—临床医学]