机构地区:[1]南昌大学第一附属医院眼科,江西省南昌市330006 [2]南昌市第三医院内分泌科,江西省南昌市330009 [3]南华大学附属第一医院眼科,湖南省衡阳市421001 [4]广州医学院第二附属医院眼科,广东省广州市510260
出 处:《眼科新进展》2012年第1期40-43,共4页Recent Advances in Ophthalmology
基 金:国家自然科学基金(编号:81160118);江西省科技支撑计划项目(编号:20111BBG70026-2);广东省高校优秀青年创新人才培养计划(编号:LYM10112);江西省卫生厅资助项目(编号:20121026)~~
摘 要:目的探讨艾炙风池穴联合遮盖疗法用于单眼弱视儿童的治疗效果。方法采用前瞻性随机对照研究方法,将2007年1月至2011年1月在我院眼科门诊确诊为单眼弱视患儿96例(96眼,年龄7~14岁)随机分为两组:A组使用红光闪烁、光栅、光刷、后像及艾炙风池穴联合遮盖治疗48例,B组使用红光闪烁、光栅、光刷、后像联合遮盖治疗48例。分别在治疗前及治疗后5d、60d、90d检测视力和治疗后60d检查视觉诱发电位,治疗前、后及两组间均进行统计学分析。结果两组在年龄、病程方面差异均无统计学意义(F=1.88、0.82,均为P>0.05)。治疗前,两组视力之间差异无统计学意义(F=0.38,P>0.05);治疗后60d,两组视力对比治疗前均有明显提高(FA=11.76,FB=7.42;均为P<0.05);两组视力之间差异也有统计学意义(F=12.80,P<0.05)。A组治疗后42眼有效(基本治愈18眼,有效24例),总有效率为87.5%;B组治疗后28眼有效(基本治愈6眼,有效22眼),总有效率58.3%;两组间总有效率差异有统计学意义(χ2=6.12,P<0.05)。治疗后60d,两组在较高空间频率下棋盘格翻转视觉诱发电位P100峰潜伏期均有缩短,A组缩短更为明显[4周/度时,治疗前、后P100峰潜伏期分别为(112.94±2.16)ms和(107.20±1.18)ms,tA(47)=12.26,P<0.05;8周/度时,治疗前、后P100峰潜伏期分别为(116.02±3.28)ms和(109.35±1.35)ms,tA(47)=10.86,P<0.05]。结论艾炙风池穴联合遮盖疗法可显著改善单眼弱视儿童的视力和视觉诱发电位,具有重要的临床应用价值。Objective To investigate the efficacy of moxibustion at Fengchi acupoint and occlusion treatment for children with simple amblyopic eye.Methods It was a prospective random controlled study.Totally 96 children diagnosed as simple amblyopic eye(aged from 7 years to 14 years) in our hospital from January 2007 to January 2011 were randomly divided into two groups:group A(moxibustion) and group B,48 cases in each group.All groups had been added with red light flicker,luster,light brush,after image combined with occlusion therapy,in addition the moxibustion was performed in group A.Visual acuity were examined at pre-therapy and 5 days,60 days,3 months after therapy and visual evoked potentials(VEP) were detected at pre-therapy and 60 days after therapy.The results were statistical analyzed.Results There was no statistical difference in age,course and visual acuity between two groups(F=1.88,0.82,0.38;all P0.05).At 60 days after therapy,compared with those of pre-therapy,the visual acuity in two groups had been improved(FA=11.76,FB=7.42;all P0.05);The visual acuity between two groups had significantly difference(F=12.80,P0.05).The total effective power in group A(healing;18 eyes;effective:24 cases) was 87.5%,and in group B was 58.3%(healing:6 eyes;effective:22 eyes),there was statistical difference(χ2=6.12,P0.05).The latency of P100 of VEP elicited by reversing checkerboard with middle to high spatial frequencies was significantly shortened in two groups at 60 days after therapy compared with those of pre-therapy,that in group A was more obvious,which were(112.94±2.16)ms and(107.20±1.18)ms before and after therapy at 4 period/radian[tA(47)=12.26,P0.05],(116.02±3.28)ms and(109.35±1.35)ms at 8 period/radian[tA(47)=10.86,P0.05].Conclusion Moxibustion at Fengchi acupoint and occlusion treatment is effective and reliable therapeutic tool for children with simple amblyopic eye,and it should be widely applied in clinical treatment.
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