脑梗死患者同型半胱氨酸血脂检测的意义  

Significance of the Measurement of Blood Homocysteine and Lipids in Patients with Cerebral Infarction

作　　者：孙旦晖[1] 张帆[1] 孙亚楠[1] 钱华[1] 

机构地区：[1]南京医科大学附属脑科医院,江苏南京210029

出　　处：《医学临床研究》2011年第12期2262-2264,共3页Journal of Clinical Research

摘　　要：[目的]研究血清同型半胱氨酸（HCY）检测对脑梗死患者的诊断意义,探讨脑梗死与HCY、血脂、血糖（GLU）及血浆纤维蛋白原（Fg）的关系.[方法]测定分析98例脑梗死患者及40例正常健康体检人群血清HCY、甘油三酯（TG） 、总胆固醇（TC）、高密度脂蛋白胆固醇 （HDL-C）、低密度脂蛋白胆固醇（LDL-C）、GLU及Fg.[结果]脑梗死组的血清TC、血浆Fg水平与对照组相比无显著差异（P〉0.05）,脑梗死组血清HCY、TG、LDL-C、GLU水平显著高于对照组（P〈0.05）,脑梗死组的血清HDL结果显著低于对照组（P〈0.01）.[结论]脑梗死与HCY升高关系密切.[Objective] To study the significance of the detection of serum homocysteine（HCY） for the diagnosis of cerebral infarction and explore the correlation of cerebral infarction with HCY, lipids, blood glucose（GLU） and plasma fibrinogen（Fg）. [Methods] Serum HCY, triglyeeride（TG）, total cholesterol（TC）, high-density lipoprotein eholesterol（HDL-C）, low-density lipoprotein cholesterol（LDL-C）, GLU and Fg in 98 cases of cerebral in- farction and 40 healthy people were measured. [Results] There were no significant differences in serum TC and plasma Fg between cerebral infarction group and control group（ P 〉0.05）. The levels of serum HCY, TG, LDL- C and GLU in cerebral infarction group were obviously higher than those in control group, and there were significant differences（ P 〈0.05）. The level of serum HDL-C in cerebral infarction was obviously lower then that in control group, and there was very significant difference（ P 〈0.01）. [Conclusion] Cerebral infarction is closely correlated with the increasing of HCY.

关 键 词：脑梗塞/血液 半胱氨酸/血液 脂类/血液 

分 类 号：R743.33[医药卫生—神经病学与精神病学]