气质联用色谱法和超高效液相色谱法检测无花果叶提取物的化学成分  

Analysis of Ficus Carica Leaves Extraction by GC-MS and UHPLC/DAD

作　　者：张吟[1] 陈一农[1] 许秋霞[1] 庄奕筠[1] 

机构地区：[1]福建医科大学第二临床医学院药剂科临床药学室,泉州362000

出　　处：《福建医科大学学报》2011年第6期423-426,共4页Journal of Fujian Medical University

基　　金：福建省教育厅课题(JA07097)

摘　　要：目的检测无花果叶提取物的化学成分。方法采用气相色谱-质谱联用(GC-MS)检测无花果叶提取物中的挥发性成分,采用超高效液相色谱法(UHPLC)检测无花果叶提取物中的芦丁。结果 GC-MS分离出16个成分,鉴定出13个成分,其中9个为新发现的成分。UHPLC鉴定出芦丁,并进行了含量测定。结论无花果叶提取物的主要成分为芦丁、补骨脂素、佛手苷内酯。Objective To analyse the chemical constituents of Ficus carica leaves extraction.Methods The volatile constituents of Ficus carica leaves extraction was analysed by GC-MS,while rutin was determined by UHPLC/DAD.Results 16 constituents were acquired while 13 were identified by GC/MS,in which 9 constituents were found for the first time.Rutin was identified and quantitated by UHPLC/DAD.Conclusion The main chemical constituents of Ficus carica leaves extraction were Lutin,7H-Furo[3,2-g]／benzopyran-7-one and 7H-Furo[3,2-g]／benzopyran-7-one,4-methoxy.

关 键 词：无花果 植物提取物 色谱法 高压液相 芦丁 补骨脂素 佛手 佛手内酯 气相色谱-质谱法 

分 类 号：R284.1[医药卫生—中药学]