农村维吾尔族成人慢性牙周炎与高血压的相关性  

The association between chronic periodontitis and hypertension in rural adult Uygur residents

作　　者：张丽[1] 李玉芳[1] 梁照忠 巴鹏飞 桑晓红[1] 刘健[1] 地里木拉提·阿不都拉[1] 王文莉[1] 

机构地区：[1]新疆医科大学第一附属医院肾病科内科重点学科,乌鲁木齐830054 [2]乌鲁木齐市口腔医院特诊科

出　　处：《中华心血管病杂志》2011年第12期1140-1144,共5页Chinese Journal of Cardiology

基　　金：国家自然科学基金项目（3060069）;新疆维吾尔自治区重点学科（内科学）基金项目（2004-2008）

摘　　要：目的探讨农村维吾尔族成人慢性牙周炎与高血压的相关性。方法采用分层随机抽样的方法从新疆维吾尔自治区墨玉县364个自然村按容量比例概率抽样，随机抽取1415名维吾尔族成人（≥18岁），进行问卷调查、体格测量、实验室检查及口腔检查。依据慢性牙周炎的诊断标准，将调查对象分为牙周炎组和非牙周炎组，其中牙周炎组按其严重程度进一步分为：轻度牙周炎组，中度牙周炎组和重度牙周炎组。牙周炎与高血压的关系采用Spearman相关分析。应用logistic回归模型对高血压相关影响因素进行分析。结果慢性牙周炎患病粗率为66．0％（934／1415），高血压患病粗率为33．8％（478／1415），非牙周炎及轻度、中度、重度牙周炎组高血压的患病比例为18．7％（90／481），35．1％（131／373），32．3％（62／192），52．8％（195／369）。Spearman相关分析结果显示牙周炎与高血压呈正相关（rs=0．273，P〈0．01）。校正年龄、性别、体质指数、腰围、糖代谢异常、高脂血症、慢性肾脏病后，多因素logstic回归分析显示牙周炎组高血压患病风险为非牙周炎组的1．75倍（OR=1．75，95％CI：1．30～2．36，P〈0．01），轻度牙周炎组高血压患病风险为非牙周炎组的1．76倍（OR=1．76，95％CI：1．26～2．48，P〈0．01），中度牙周炎组高血压患病风险为非牙周炎组的1．21倍（OR=1．21，95％CI：0．80～1．84，P〉0．05），重度牙周炎组高血压患病风险为非牙周炎组的2．26倍（OR=2．26，95％CI：1．57—3．26，P〈0．01）。结论农村维吾尔族成人慢性牙周炎与高血压独立相关。Objective To explore the association between chronic periodontitis and hypertension in rural adult Uygur residents. Methods A total of 1415 Uygur residents aged 18 and over were selected by random multistage and probability proportional to size from 364 villages in Moyu county of Xinjiang Uygur autonomous region, all subjects received questionnaire, physical examination and biochemical analysis and oral examination. The subjects were categorized as periodontitis group and no pefiodontitis group, the periodontitis group was further categorized as mild, moderate and severe periodontitis subgroup. The relationship between chronic periodontitis with hypertension was analyzed by Spearman correlation. Binary logistic regression was used to calculate the influential factors for hypertension. Results The prevalence rates of chronic periodontitis and hypertension were 66. 0% （934/1415） and 33.8% （478/1415）, respectively. The prevalence rates of hypertension were 18.7% （90/481）, 35.1% （ 131/373 ）, 32. 3% （62/192）, 52. 8% （ 195/369 ） in no periodontitis, mild, moderate and severe periodontitis groups, respectively. Spearman correlation showed an association of chronic periodontitis with hypertension （rs = 0.273, P 〈 0.01 ） .After adjustment for age, gender, body mass index, waist circumference, glycometabolism disorder, hyperlipidemia, chronic kidney disease, multiple logistic regression analysis showed that periodontitis was significantly associated with hypertension （OR = 1.75, 95% CI： 1.30 -2. 36, P 〈 0. 01 ）. Compared with no periodontitis, mild （ OR = 1.76, 95 % CI： 1.26 - 2.48, P 〈 0. 01 ） and severe （ OR =2. 26,95% CI. 1.57 - 3.26, P 〈 0. 01 ） periodontitis were significantly associated with hypertension while moderate periodontitis was not significantly associated with hypertension （OR = 1.21, 95% CI： 0. 80 - 1.84, P 〉 0. 05 ）. Conclusion This study showed an independent association of periodontitis with hypertension in this study cohort.

关 键 词：牙周炎 高血压 农村人口 

分 类 号：R781.4[医药卫生—口腔医学] R544.1[医药卫生—临床医学]