中药清毒栓对宫颈上皮内瘤变Ⅰ、Ⅱ级患者血清SccAg的影响  

Impact of Qingdu Suppository(QDS) on serum of SccAg in CINⅠand CIN-Ⅱ

作　　者：林芳[1] 

机构地区：[1]浙江省杭州市余杭区第二人民医院妇产科,浙江杭州311121

出　　处：《中国农村卫生事业管理》2011年第12期1313-1314,共2页Chinese Rural Health Service Administration

摘　　要：目的:探讨中药清毒栓对宫颈上皮内瘤变(C IN)Ⅰ、Ⅱ级患者血清SccA g的影响。方法:92例C IN-Ⅰ、Ⅱ确诊患者随机分为治疗组和对照组各46例,两组均分别给予清毒栓和-α2b干扰素塞阴治疗20天、40天及60天,分别抽取以上患者的用药前及用药各阶段后晨起空腹血,M E IA法测定血清中SccA g值。结果:1、用药20天时患者两组血清SccA g的含量与用药前比有降低趋势,但无统计学意义。2、用药40天时患者两组血清SccA g的含量与用药前比有明显降低(P<0.05)。3、用药60天后两组患者血清SccA g的含量与用药40天比有降低的趋势,但效果不显著(P>0.05),无统计学意义。4、清毒栓组比-α2b干扰素组血清SccA g的含量略见降低,但无统计学意义。结论:中药清毒栓对C IN-Ⅰ、Ⅱ级患者有一定的预防和治疗作用,可体现在对血清SccA g的含量变化上,值得临床医生推广应用。Objective To investigate the effect of Qingdu Suppository（QDS） on serum of SccAg in CIN-Ⅰand CIN-Ⅱ.Methods 92 cases of CIN-Ⅰand CIN-Ⅱ were divided randomly into two group（46 cases for each group） and treated by QDS and α-2b interferon for 20 days,40 days and 60 days.Limosis serum of each patient was taken before and after treatment.A micropartical enzyme immunoassay（MEIA） was performed to measure the concentrations of Scc-Ag.Results At 20th day,SCCAg level was reduced compared with that before treatment,but without statistical significance.At 40th day,SCCAg level was significantly lower than that before treatment（P0.05）.At 60th day,SCCAg level had a tendency of decrease compared with that at the 40th day,but without obvious effect and significant meaning（P0.05）.SCCAg level in experimental group was a bit lower than that of the comparison group,but without statistical signifance（P0.05）.Conclusion Impact of QDS on serum of SccAg in CIN-Ⅰand CIN-Ⅱ was affirmed.

关 键 词：清毒栓 宫颈上皮内瘤变 SCCAG 

分 类 号：R737.33[医药卫生—肿瘤]