17578例宫颈液基细胞学筛查结果分析  

Clinical analysis on 17578 cases of cervical cytology liquid-based screening results

作　　者：徐小敏[1] 余晓[1] 夏利花[1] 

机构地区：[1]浙江省衢州市人民医院妇科,浙江衢州324000

出　　处：《中国现代医生》2012年第1期24-26,共3页China Modern Doctor

基　　金：浙江省卫生厅科技立项项目(2010SSA011);浙江省衢州市科技立项项目(20101088)

摘　　要：目的探讨液基细胞学(TCT)技术在宫颈病变筛查中的临床应用价值。方法选择本院2009年1月～2010年12月进行宫颈TCT检查的患者17 578例,按照Bethesda系统(TBS)分类法进行细胞学诊断,对其中发现细胞学异常的患者行阴道镜下活检,对比分析宫颈细胞学和组织学检查结果,并对其中组织学异常患者进行社会人口学调查。结果17 578例液基细胞学检查结果中ASC-US以上病例为1 280例,阳性检出率为7.28%,其中LSIL确诊为湿疣和CINⅠ共179例,HSIL确诊为CINⅡ、Ⅲ38例;ASC-US、ASC-H和AGC确诊为湿疣和CIN共141例(其中CINⅡ和Ⅲ7例)。50岁以上、农村及无业人员、暂住人口以及小学及以下文化人群中CINⅡ、Ⅲ级的比例较其他人群显著增高(P<0.05)。结论TCT技术在宫颈癌筛查中的准确度较高,是一种有效的宫颈疾病筛查方法,针对高危人群进行重点筛查,并对其中异常患者行组织学确诊可有效降低宫颈癌的发生率。Objective To study the liquid-based cytology （TCT） technology in screening for cervical lesions in the clinical application. Methods All 17 578 cases with cervical TCT inspection conducted were selected in our hospital from January 2009 to December 2010, according to Bethesda system （TBS） for cytology classifications, of which discovered in patients with abnormal cytology colposcopy and biopsy, compared the cervical cytology and histology results, and histological abnormalities among patients with socio-demograpbic surveys. Results There were 1 280 cases in 17 578 cases of liquid-based cytology results of ASC-US or more, the positive detection rate was 7.28%, which LSIL diagnosis of condyloma and CIN I were 179 cases, HSIL diagnosed as CIN Ⅱ、Ⅲ were 38 cases;ASC- US, ASC-H and AGC diagnosed as condyloma and CIN were 141 cases （including CIN Ⅱand Ⅲ7 cases）. Women over the age of 50 rural and unemployed, as well as temporary residents in the primary and the following cultural groups CINⅡ、Ⅲgrade percentage was significantly higher than other groups （P〈0.05）. Conclusion TCT technology in cervical cancer screening in the high degree of accuracy, is an effective method of screening for cervical disease, to focus on screening for high-risk groups, and among patients with abnormal histological diagnosis can effectively reduce the incidence of cervical cancer.

关 键 词：液基细胞学 宫颈疾病 活检 组织病理学 社会人口学 

分 类 号：R737.33[医药卫生—肿瘤]