血清C反应蛋白在肝硬化腹水合并感染中的临床意义  

Clinical significance of C reactive protein in liver cirrhosis patients complicating infection with ascites

作　　者：王晓[1] 朱均权 

机构地区：[1]浙江省嵊州市人民医院检验科,浙江嵊州312400

出　　处：《中国现代医生》2012年第1期54-55,58,共3页China Modern Doctor

摘　　要：目的探讨血清C反应蛋白(CRP)在肝硬化腹水合并感染中的临床意义。方法检测106例肝硬化患者CRP、WBC和GR百分率(GR%),计算合并感染和继发感染者各指标的阳性率。结果合并感染组和继发感染组CRP、WBC和GR%水平分别显著高于未合并感染组和无继发感染组(P<0.01);合并感染组和继发感染组抗感染治疗后3 d和7 d,三者水平分别显著低于抗感染治疗前和治疗后3 d(P<0.01)。治疗前、治疗后3 d和治疗后7 d CRP阳性率均显著高于WBC和GR%阳性率(P<0.01)。结论检测CRP对肝硬化腹水患者感染的进展及抗感染疗效判断具有重要意义。Objective To explore the clinical significance of serum C reactive protein （CRP） in liver cirrhosis patients complicating infection with ascites. Methods The levels of CRP, white blood cell （WBC） and granulocyte percent （GR%） in 106 patients with liver cirrhosis were determined, the positive percent was calculated in patients of infection-complicating and secondary infection. Results At infection-complicating group and secondary infection group, the levels of CRP, WBC and GR% were significantly higher than those at non-infection-complicating group and non-secondary infection group, respectively （P〈0.01） After 3 and 7 days of anti- microbe therapy, the levels of CRP, WBC and GR% were remarkedly lower than those before therapy and after 3 days of therapy, respectively, at infection complicating group and secondary infection group （P〈0.01）. Before therapy,after 3 days and 7 days of therapy, the positive percent of CRP was markedly higher than that of WBC and GR% （P〈0.01）. Conclusions It is valuable for the change of CRP to evaluate the occlurence, development and therapeutical effect of infection in liver cirrhosis patients with ascites.

关 键 词：肝硬化 腹水 感染 C反应蛋白 

分 类 号：R575.2[医药卫生—消化系统]