埃索美拉唑治疗胃食管反流病疗效观察  

Investigating the clinical efficacy and safety of treatment of gastroesophageal reflux esomeprazole

作　　者：秦海春[1] 

机构地区：[1]云南省第一人民医院消化科,云南昆明650032

出　　处：《中国现代医生》2012年第2期54-55,共2页China Modern Doctor

摘　　要：目的探讨埃索美拉唑治疗胃食管反流临床疗效及安全性。方法将2010年6月～2011年6月在我院接受治疗的92例GERD患者随机分为观察组和对照组，两组均给予常规治疗，观察组在常规治疗基础上给予埃索美拉唑口服治疗，对照组给予奥美拉唑口服治疗，观察两组患者治疗4周后临床疗效。结果观察组治疗后烧心、反酸、胸骨后疼痛症状积分明显低于对照组，组间比较有显著差异（P〈0．05）；观察组有效率为95，65％，明显高于对照组的76．09％，组间比较有显著差异（P〈0．05）。结论埃索美拉唑治疗GERD具有抑酸能力强、药效持久、不良反应少等优点，是目前治疗GERD的一种较佳药物。Objective To investigate the clinical efficacy and safety of gastroesophageal reflux esomeprazole treatment. Methods All 92 cases of GERD were randomly divided into observation group given Esomeprazole azole oral treatment on the basis of conventional therapy and control group given oral omeprazole treatment, efficacy.conventional treatment, in June 2010 - June 2011 in our hospital, were observed after 4 weeks of treatment. Results After treatment onf heartburn, acid reflux, chest pain symptom score was significantly lower than the control group between the two groups were significantly different （/9〈0.05）; observation group was 95.65%, significantly higher than 76.09% between the two groups were significantly different （P〈0.05）. Conclusion： GERD Esomeprazole treatment with acid-suppressing ability, lasting, adverse reactions, etc., is a better treatment of GERD drugs.

关 键 词：胃食管反流病 埃索美拉唑 奥美拉唑 

分 类 号：R571[医药卫生—消化系统]