PEI联合TACE治疗原发性肝癌疗效评价  

Efficacy of percutaneous ethanol injection combing with transcatherter arterial chemoembolization for hepatocellular carcinoma

作　　者：郭刚[1] 陈秋芬[1] 杨春旺[1] 

机构地区：[1]山东省济南市第三人民医院放射科,山东济南250101

出　　处：《海南医学院学报》2012年第1期77-79,共3页Journal of Hainan Medical University

基　　金：海南医学院科研基金资助学报项目(0020120022)~~

摘　　要：目的:探讨原发性肝癌的有效治疗方法。方法:120例原发性肝癌患者,随机分为两组,观察组60例采用经皮肝穿刺无水乙醇注射(percutaneous ethanol injection,PEI)联合肝动脉化疗术(tran-scatherter arterial chemoembolization,TACE),对照组60例行单纯TACE治疗。治疗2个疗程后复查两组患者CT;随访2年,记录并比较两组治疗后6个月、12个月、18个月、24个月生存率。结果:PEI联合TACE观察组生活质量较高,两组肿瘤缩小率及生存率比较差异均有统计学意义(P均<0.05)。结论:PEI联合TACE能有效延长患者的生存期,提高患者生存质量,其临床疗效明显优于单纯TACE治疗,是原发性肝癌综合治疗的安全、经济、有效方案。Objective：To explore an effective treatment for hepatocellular carcinoma.Methods：A total of 120 hepatocellular carcinoma patients were randomly divided into two groups.The treatment group（60 patients） was treated by percutaneous ethanol injection（PEI） combing with transcatherter arterial chemoembolization（TACE）,while the control group（60 cases） was treated by TACE alone.After 2 courses of treatment,CT was applied on both groups.Follow up were conducted on for 2 years to observe and compare the 6,12,18,24 months survival rates between the two groups.Results：Patients of the treatment group had higher quality of life than that of the control group.Besides,there were significant differences in reduced size of tumors and survival rate between the two groups（P0.05）.Conclusions：The combination of PEI and TACE is a safe,economic and effective treatment for hepatocellular carcinoma,which can prolong the survival time and improve patients＇ life quality.

关 键 词：原发性肝癌 无水乙醇 肝动脉 栓塞治疗 

分 类 号：R73[医药卫生—肿瘤]