肺外小细胞癌的诊断和治疗  

Diagnosis and treatment of extrapulmonary small cell cancer

作　　者：孙红梅[1] 陈文彰[1] 燕丽香[1] 常中飞[1] 鲍云华[2] 

机构地区：[1]北京石景山医院肿瘤科,北京100043 [2]解放军第307医院肿瘤科,北京100071

出　　处：《中华老年多器官疾病杂志》2011年第5期474-477,共4页Chinese Journal of Multiple Organ Diseases in the Elderly

摘　　要：小细胞癌(SCC)是临床和病理上具有明显特征的一组疾病。最常见的发病部位是肺,但体内其他器官也时有发生,这就是肺外小细胞癌(EPSCC)。EPSCC的好发部位是胃肠道、头颈部以及泌尿生殖系统,也有些病例原发灶不明。EPSCC的发生率很低,因此缺乏大样本的随机临床研究资料。EPSCC同小细胞肺癌(SCLC)具有相似的临床病理学特征,对于EPSCC的治疗,大部分临床医生借鉴SCLC的治疗方法。然而,不同部位的EPSCC临床过程以及远处转移的发生率又与SCLC不同,治疗方案又不尽相同。本文就不同部位的EPSCC国内外治疗进展作一综述,供临床医师参考。Small cell cancer（SCC） is a distinct clinicopathological entity.Although it has commonly pulmonary origin,SCC may also originate in extrapulmonary organs,including gastrointestinal tract,head and neck region,urogenital system,and occasionally unknown primary origin,which is known as extrapulmonary small cell cancer（EPSCC）.Given the rarity of the disease,no large-sized randomized trial has been performed to guide the treatment of patients with EPSCC.This lack of data and its pathological similarity to the small cell lung cancer（SCLC） led most investigators to adopt similar principles of SCLC to the treatment of EPSCC.However, difference of clinical course and frequency of distant metastases warrant differential therapeutic approaches.In this paper,we reviewed the available data concerning the treatment of EPSCC originated at different sites.

关 键 词：肺外小细胞癌 治疗 癌 小细胞 

分 类 号：R730.4[医药卫生—肿瘤] R730.5[医药卫生—临床医学]