自配止痛口服液治疗放射性食管炎临床观察  

Curative Effect Observation of Radioactive Esophagitis Treated with Home-made Pain Killing Mixture

作　　者：刘粉霞[1] 王景花[2] 蒋美萍[3] 

机构地区：[1]河南省安阳市疾病预防控制中心,455000 [2]安阳市肿瘤医院,455000 [3]昆明云南省肿瘤医院,650118

出　　处：《中国医疗前沿》2011年第23期45-46,共2页China Healthcare Innovation

摘　　要：目的通过临床应用自配止痛口服液治疗放射性食管炎观察其疗效及副反应。方法 2009年8月-2011年6月,胸部肿瘤需放射治疗患者120例,将其随机分为观察组和对照组各60例。观察组放疗1周开始服用自配口服液(0.9%NaCL250ml+地塞米松注射液10mg+庆大霉素注射液40万u+5%利多卡因10ml),3-5次/d,20-30ml/次,缓慢吞下,连服2-3周。对照组在放疗过程中出现吞咽困难伴疼痛等放射性食管炎症状时,给予静脉滴注抗菌素+糖皮质激素治疗,必要时服用止痛药物。结果在胸部肿瘤放疗中对放射性食管炎的治疗,观察组(口服)与对照组(静脉)疗效比较无显著差异。结论用药途径选用口服是治疗放射性食管炎的首选;此方法即安全、费用低、起效快、使用方便,遵循用药途径规律,值得临床推广应用。Objective To study effective therapy of radioactive esophagitis.Methods One hundred and twenty thoracic tumor patients trested with radiotherapy were selected and divided into therapy group and control group at random.Home-made Pain Killing Mixture（normal saline 250ml＋400000units gentamycin＋10mg Dexamcthasone＋10ml 5% lidocaine） was immedately given to those who have radiotherapeutic reactions in therapy group,while in control group,antibiotics and glucocorticoid therapy were given by intravenous drip.Results There was no statistic difference in clinical curative effect between therapy group and control group.Conclusion To use home-made pain killing mixture is a highly effective,safe,effective,convenient and inexpensive way,the first choice of treatment for radioactive esophagitis.

关 键 词：放射性食管炎 用药途径 自配口服液 

分 类 号：R735.1[医药卫生—肿瘤]